STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
AB434_2002Hypothetical protein. (839 aa)    
Predicted Functional Partners:
AB434_1482
4,4'-diaponeurosporenoate glycosyltransferase.
  
 
 0.785
htpG
Chaperone protein HtpG; Molecular chaperone. Has ATPase activity.
  
 0.773
AB434_2004
Sorbitol dehydrogenase.
 
 
 
 0.758
AB434_2111
Flagellar protein.
   
 0.757
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
   
 0.754
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.743
AB434_2850
Stage V sporulation protein whose disruption leads to the production of immature spores (SpoVK).
  
 0.738
AB434_3856
NAD-independent protein deacetylase AcuC.
    
 0.737
AB434_4011
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
  
 
 0.694
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
   0.681
Your Current Organism:
Bacillus coagulans
NCBI taxonomy Id: 1398
Other names: ATCC 7050, B. coagulans, BCRC 10606, Bacillus sp. NCIM 2323, CCM 2013, CCRC 10606, CCRC:10606, CCUG 7417, CFBP 4225, CIP 66.25, DSM 1, IFO 12583, IMET 10993, JCM 2257, LMG 6326, LMG:6326, Lactobacillus sp. T4, NBRC 12583, NCAIM B.01086, NCCB 48014, NCCB 77025, NCIB 9365, NCIMB 9365, NCTC 10334, NRRL NRS-609, VKM B-731
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