node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AB434_0998 | AB434_2176 | AB434_0998 | AB434_2176 | Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria; May function as heme-dependent peroxidase. | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.694 |
AB434_0998 | AB434_2272 | AB434_0998 | AB434_2272 | Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria; May function as heme-dependent peroxidase. | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.704 |
AB434_0998 | ctaA | AB434_0998 | AB434_2553 | Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria; May function as heme-dependent peroxidase. | Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily. | 0.625 |
AB434_0998 | hemE | AB434_0998 | AB434_2270 | Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria; May function as heme-dependent peroxidase. | Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.438 |
AB434_0998 | hemH | AB434_0998 | AB434_2271 | Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria; May function as heme-dependent peroxidase. | Ferrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.983 |
AB434_2110 | AB434_2176 | AB434_2110 | AB434_2176 | Competence protein F. | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.533 |
AB434_2110 | AB434_2272 | AB434_2110 | AB434_2272 | Competence protein F. | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.533 |
AB434_2176 | AB434_0998 | AB434_2176 | AB434_0998 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria; May function as heme-dependent peroxidase. | 0.694 |
AB434_2176 | AB434_2110 | AB434_2176 | AB434_2110 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Competence protein F. | 0.533 |
AB434_2176 | AB434_2272 | AB434_2176 | AB434_2272 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.912 |
AB434_2176 | AB434_3676 | AB434_2176 | AB434_3676 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.466 |
AB434_2176 | ctaA | AB434_2176 | AB434_2553 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily. | 0.507 |
AB434_2176 | hemC | AB434_2176 | AB434_3677 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.506 |
AB434_2176 | hemE | AB434_2176 | AB434_2270 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.993 |
AB434_2176 | hemH | AB434_2176 | AB434_2271 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Ferrochelatase, protoheme ferro-lyase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.991 |
AB434_2272 | AB434_0998 | AB434_2272 | AB434_0998 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Hemoprotein HemQ, essential component of heme biosynthetic pathway in Gram-positive bacteria; May function as heme-dependent peroxidase. | 0.704 |
AB434_2272 | AB434_2110 | AB434_2272 | AB434_2110 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Competence protein F. | 0.533 |
AB434_2272 | AB434_2176 | AB434_2272 | AB434_2176 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.912 |
AB434_2272 | AB434_2273 | AB434_2272 | AB434_2273 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | TetR family transcriptional regulator. | 0.424 |
AB434_2272 | AB434_3676 | AB434_2272 | AB434_3676 | Protoporphyrinogen IX oxidase, aerobic, HemY; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.448 |