STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KML46211.1Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (492 aa)    
Predicted Functional Partners:
KML46471.1
Stage III sporulation protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.850
KML46042.1
Stage III sporulation protein AD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.838
KML46462.1
Stage II sporulation protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.836
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.819
KML38760.1
Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.813
gpr
Peptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
   
 0.809
KML46045.1
Stage III sporulation protein AA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.808
KML45957.1
Stage V sporulation protein AC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.807
KML46644.1
Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.806
KML46023.1
Chemotaxis protein CheY; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.806
Your Current Organism:
Bacillus firmus
NCBI taxonomy Id: 1399
Other names: ATCC 14575, B. firmus, BCRC 11730, Bacillaceae bacterium HQ2, Bacillus sp. JP44SK20, Bacillus sp. LK28, Bacillus sp. NCIM 2264, Bacillus sp. NCIM 2462, CCM 2213, CCRC 11730, CCRC:11730, CCUG 7418, CIP 52.70, DSM 12, IAM 12464, IFO 15306, JCM 2512, LMG 7125, LMG:7125, NBRC 15306, NCAIM B.01087, NCCB 48015, NCIB 9366, NCIMB 9366, NCTC 10335, NRRL B-14307, NRRL NRS-613, VKM B-498
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