Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KML42817.1Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)    
Predicted Functional Partners:
KML42123.1
General stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.755
KML39819.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
  
  
 0.678
KML45387.1
Universal stress protein UspA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal stress protein A family.
 
   
 0.677
KML42829.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.647
rsbW
Serine/threonine protein kinase; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
   
    0.600
KML40322.1
Cysteine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.546
KML39967.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.450
KML38097.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.450
KML46278.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
   
    0.424
KML41729.1
Cysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.424
Your Current Organism:
Bacillus firmus
NCBI taxonomy Id: 1399
Other names: ATCC 14575, B. firmus, BCRC 11730, Bacillaceae bacterium HQ2, Bacillus sp. JP44SK20, Bacillus sp. LK28, Bacillus sp. NCIM 2264, Bacillus sp. NCIM 2462, CCM 2213, CCRC 11730, CCRC:11730, CCUG 7418, CIP 52.70, DSM 12, IAM 12464, IFO 15306, JCM 2512, LMG 7125, LMG:7125, NBRC 15306, NCAIM B.01087, NCCB 48015, NCIB 9366, NCIMB 9366, NCTC 10335, NRRL B-14307, NRRL NRS-613, VKM B-498
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