node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ETZ06716.1 | ETZ06719.1 | P618_201122 | P618_201125 | Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.613 |
ETZ06716.1 | ETZ07691.1 | P618_201122 | P618_200100 | Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | 0.996 |
ETZ06716.1 | ETZ07764.1 | P618_201122 | P618_200035 | Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside diphosphate kinase. | 0.813 |
ETZ06716.1 | ETZ07770.1 | P618_201122 | P618_200010 | Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thiol-disulfide oxidoreductase. | 0.885 |
ETZ06716.1 | dut | P618_201122 | P618_201056 | Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.849 |
ETZ06716.1 | polA | P618_201122 | P618_201141 | Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.775 |
ETZ06716.1 | tmk | P618_201122 | P618_200238 | Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.846 |
ETZ06719.1 | ETZ06716.1 | P618_201125 | P618_201122 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.613 |
ETZ06719.1 | ETZ07691.1 | P618_201125 | P618_200100 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | 0.545 |
ETZ06719.1 | dut | P618_201125 | P618_201056 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.707 |
ETZ06719.1 | polA | P618_201125 | P618_201141 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
ETZ07478.1 | ETZ07691.1 | P618_200319 | P618_200100 | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | 0.639 |
ETZ07487.1 | ETZ07691.1 | P618_200329 | P618_200100 | Protein MurJ homolog. | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | 0.401 |
ETZ07691.1 | ETZ06716.1 | P618_200100 | P618_201122 | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | Putative ribonucleoside-diphosphate reductase large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.996 |
ETZ07691.1 | ETZ06719.1 | P618_200100 | P618_201125 | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.545 |
ETZ07691.1 | ETZ07478.1 | P618_200100 | P618_200319 | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | 0.639 |
ETZ07691.1 | ETZ07487.1 | P618_200100 | P618_200329 | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | Protein MurJ homolog. | 0.401 |
ETZ07691.1 | ETZ07764.1 | P618_200100 | P618_200035 | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | Nucleoside diphosphate kinase. | 0.586 |
ETZ07691.1 | ETZ07770.1 | P618_200100 | P618_200010 | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | Thiol-disulfide oxidoreductase. | 0.836 |
ETZ07691.1 | dut | P618_200100 | P618_201056 | UPF0301 protein BBta_6966; Belongs to the UPF0301 (AlgH) family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.480 |