STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CR51_08730Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (172 aa)    
Predicted Functional Partners:
CR51_08725
Curli production assembly/transport protein CsgG; Involved in the stability of the curlin proteins during assembly; involved in the secretion of the major curlin subunit CsgA across the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.830
CR51_08720
Curli assembly protein CsgF; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.813
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.771
parE
DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.771
CR51_39990
Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.717
CR51_17345
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.685
CR51_31620
Guanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.665
CR51_40710
Guanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.665
CR51_18310
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.662
CR51_26460
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
    
  0.654
Your Current Organism:
Caballeronia megalochromosomata
NCBI taxonomy Id: 1399969
Other names: Burkholderia megalochromosomata, Burkholderia megalochromosomata Baek et al. 2015, Burkholderia sp. JC2949, C. megalochromosomata, Caballeronia megalochromosomata (Baek et al. 2015) Dobritsa and Samadpour 2016, JCM 19905, KACC 17925, strain JC2949
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