node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CR51_02230 | CR51_24240 | CR51_02230 | CR51_24240 | D-amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.497 |
CR51_02230 | CR51_25555 | CR51_02230 | CR51_25555 | D-amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.841 |
CR51_02230 | CR51_32425 | CR51_02230 | CR51_32425 | D-amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.719 |
CR51_02230 | CR51_39415 | CR51_02230 | CR51_39415 | D-amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.646 |
CR51_02230 | ilvC | CR51_02230 | CR51_01205 | D-amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.568 |
CR51_02230 | ilvE | CR51_02230 | CR51_26480 | D-amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.657 |
CR51_02230 | leuA-2 | CR51_02230 | CR51_16080 | D-amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.797 |
CR51_20635 | CR51_24240 | CR51_20635 | CR51_24240 | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.497 |
CR51_20635 | CR51_25555 | CR51_20635 | CR51_25555 | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.835 |
CR51_20635 | CR51_32425 | CR51_20635 | CR51_32425 | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.636 |
CR51_20635 | CR51_39415 | CR51_20635 | CR51_39415 | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.698 |
CR51_20635 | ilvC | CR51_20635 | CR51_01205 | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.608 |
CR51_20635 | leuA-2 | CR51_20635 | CR51_16080 | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.897 |
CR51_24240 | CR51_02230 | CR51_24240 | CR51_02230 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.497 |
CR51_24240 | CR51_20635 | CR51_24240 | CR51_20635 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.497 |
CR51_24240 | CR51_25555 | CR51_24240 | CR51_25555 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.910 |
CR51_24240 | CR51_32425 | CR51_24240 | CR51_32425 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.629 |
CR51_24240 | CR51_39415 | CR51_24240 | CR51_39415 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.874 |
CR51_24240 | ilvC | CR51_24240 | CR51_01205 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.852 |
CR51_24240 | ilvE | CR51_24240 | CR51_26480 | Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.497 |