node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CR51_05370 | CR51_32360 | CR51_05370 | CR51_32360 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.649 |
CR51_05370 | CR51_34415 | CR51_05370 | CR51_34415 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.702 |
CR51_05370 | purA | CR51_05370 | CR51_30165 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.899 |
CR51_05370 | purH | CR51_05370 | CR51_32690 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.720 |
CR51_05370 | truA | CR51_05370 | CR51_07775 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.659 |
CR51_32345 | CR51_32355 | CR51_32345 | CR51_32355 | Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | 0.670 |
CR51_32345 | CR51_32360 | CR51_32345 | CR51_32360 | Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.685 |
CR51_32345 | lnt | CR51_32345 | CR51_32365 | Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.670 |
CR51_32345 | ybeY | CR51_32345 | CR51_32350 | Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. | rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.983 |
CR51_32355 | CR51_32345 | CR51_32355 | CR51_32345 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.670 |
CR51_32355 | CR51_32360 | CR51_32355 | CR51_32360 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.473 |
CR51_32355 | ybeY | CR51_32355 | CR51_32350 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.689 |
CR51_32360 | CR51_05370 | CR51_32360 | CR51_05370 | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.649 |
CR51_32360 | CR51_32345 | CR51_32360 | CR51_32345 | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphate starvation-inducible protein PhoH; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.685 |
CR51_32360 | CR51_32355 | CR51_32360 | CR51_32355 | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | 0.473 |
CR51_32360 | CR51_34415 | CR51_32360 | CR51_34415 | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.654 |
CR51_32360 | hflX | CR51_32360 | CR51_30190 | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTPase HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.491 |
CR51_32360 | lnt | CR51_32360 | CR51_32365 | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.853 |
CR51_32360 | purA | CR51_32360 | CR51_30165 | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.701 |
CR51_32360 | purH | CR51_32360 | CR51_32690 | Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.594 |