STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ku-5DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (316 aa)    
Predicted Functional Partners:
ligD
ATP-dependent DNA ligase; Catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.911
ligD-2
ATP-dependent DNA ligase; Catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.911
ligD-4
ATP-dependent DNA ligase; Catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.911
CR51_35760
DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.911
CR51_42220
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.911
CR51_42190
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.778
CR51_01035
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.703
CR51_02110
DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.703
CR51_10610
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.703
CR51_14865
DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.703
Your Current Organism:
Caballeronia megalochromosomata
NCBI taxonomy Id: 1399969
Other names: Burkholderia megalochromosomata, Burkholderia megalochromosomata Baek et al. 2015, Burkholderia sp. JC2949, C. megalochromosomata, Caballeronia megalochromosomata (Baek et al. 2015) Dobritsa and Samadpour 2016, JCM 19905, KACC 17925, strain JC2949
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