STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
recBExodeoxyribonuclease V beta chain; Derived by automated computational analysis using gene prediction method: Protein Homology. (1146 aa)    
Predicted Functional Partners:
recC
Exodeoxyribonuclease V gamma chain; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
recD
Exodeoxyribonuclease V alpha chain; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.998
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
       0.818
recA
DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.805
ligA
NAD-dependent DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
 
 0.678
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.660
sbcD
Exonuclease sbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
  
 0.649
recJ
Single-stranded-DNA-specific exonuclease recJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.648
dnaE
DNA polymerase III alpha subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.639
sbcC
Exonuclease sbcC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.634
Your Current Organism:
Borrelia hermsii
NCBI taxonomy Id: 140
Other names: B. hermsii, Spirochaeta hermsi, strain DAH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.