node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGY53467.1 | gcvP | BRDCF_p840 | BRDCF_p155 | Putative 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | Glycine dehydrogenase; Belongs to the GcvP family. | 0.939 |
AGY53467.1 | glyA | BRDCF_p840 | BRDCF_p326 | Putative 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.913 |
AGY53467.1 | ltaE | BRDCF_p840 | BRDCF_p2308 | Putative 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | Low specificity L-threonine aldolase. | 0.909 |
bfmBC | gcvH | BRDCF_p1909 | BRDCF_p2307 | Dihydrolipoyl dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.983 |
bfmBC | gcvP | BRDCF_p1909 | BRDCF_p155 | Dihydrolipoyl dehydrogenase. | Glycine dehydrogenase; Belongs to the GcvP family. | 0.947 |
bfmBC | gcvT | BRDCF_p1909 | BRDCF_p1621 | Dihydrolipoyl dehydrogenase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.956 |
bfmBC | glyA | BRDCF_p1909 | BRDCF_p326 | Dihydrolipoyl dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.921 |
bfmBC | lpd | BRDCF_p1909 | BRDCF_p763 | Dihydrolipoyl dehydrogenase. | Dihydrolipoyl dehydrogenase. | 0.915 |
fumB | gcvP | BRDCF_p1634 | BRDCF_p155 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Glycine dehydrogenase; Belongs to the GcvP family. | 0.941 |
fumB | glyA | BRDCF_p1634 | BRDCF_p326 | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.455 |
gcvH | bfmBC | BRDCF_p2307 | BRDCF_p1909 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase. | 0.983 |
gcvH | gcvP | BRDCF_p2307 | BRDCF_p155 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT | BRDCF_p2307 | BRDCF_p1621 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvH | glyA | BRDCF_p2307 | BRDCF_p326 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.963 |
gcvH | lpd | BRDCF_p2307 | BRDCF_p763 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase. | 0.982 |
gcvH | ltaE | BRDCF_p2307 | BRDCF_p2308 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Low specificity L-threonine aldolase. | 0.612 |
gcvP | AGY53467.1 | BRDCF_p155 | BRDCF_p840 | Glycine dehydrogenase; Belongs to the GcvP family. | Putative 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase. | 0.939 |
gcvP | bfmBC | BRDCF_p155 | BRDCF_p1909 | Glycine dehydrogenase; Belongs to the GcvP family. | Dihydrolipoyl dehydrogenase. | 0.947 |
gcvP | fumB | BRDCF_p155 | BRDCF_p1634 | Glycine dehydrogenase; Belongs to the GcvP family. | Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.941 |
gcvP | gcvH | BRDCF_p155 | BRDCF_p2307 | Glycine dehydrogenase; Belongs to the GcvP family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |