ETY73373.1 protein (Lactobacillus fabifermentans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ETY73373.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)

Predicted Functional Partners:

ETY73393.1

0.762

ETY73374.1

0.566

ETY73375.1

0.535

ETY73376.1

0.535

ETY73377.1

0.498

Your Current Organism:

Lactobacillus fabifermentans

NCBI taxonomy Id: 1400520
Other names: L. fabifermentans T30PCM01, Lactobacillus fabifermentans T30PCM01

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ETY73373.1	ETY73374.1	LFAB_12785	LFAB_12795	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.566
ETY73373.1	ETY73375.1	LFAB_12785	LFAB_12800	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.535
ETY73373.1	ETY73376.1	LFAB_12785	LFAB_12805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.535
ETY73373.1	ETY73377.1	LFAB_12785	LFAB_12810	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.498
ETY73373.1	ETY73393.1	LFAB_12785	LFAB_12790	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.762
ETY73374.1	ETY73373.1	LFAB_12795	LFAB_12785	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.566
ETY73374.1	ETY73375.1	LFAB_12795	LFAB_12800	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.727
ETY73374.1	ETY73376.1	LFAB_12795	LFAB_12805	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.727
ETY73374.1	ETY73377.1	LFAB_12795	LFAB_12810	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.672
ETY73374.1	ETY73393.1	LFAB_12795	LFAB_12790	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.574
ETY73375.1	ETY73373.1	LFAB_12800	LFAB_12785	GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.535
ETY73375.1	ETY73374.1	LFAB_12800	LFAB_12795	GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.727
ETY73375.1	ETY73376.1	LFAB_12800	LFAB_12805	GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.821
ETY73375.1	ETY73377.1	LFAB_12800	LFAB_12810	GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.765
ETY73375.1	ETY73393.1	LFAB_12800	LFAB_12790	GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.542
ETY73376.1	ETY73373.1	LFAB_12805	LFAB_12785	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.535
ETY73376.1	ETY73374.1	LFAB_12805	LFAB_12795	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.727
ETY73376.1	ETY73375.1	LFAB_12805	LFAB_12800	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.821
ETY73376.1	ETY73377.1	LFAB_12805	LFAB_12810	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.714
ETY73376.1	ETY73393.1	LFAB_12805	LFAB_12790	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.542

page 1 of 2

Network Stats

number of nodes:

5

number of edges:

9

average node degree:

3.6

avg. local clustering coefficient:

0.9

expected number of edges:

9

PPI enrichment p-value:

0.39

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006259

DNA metabolic process

6 of 123

1.23

1.1

0.00069

GO:0071103

DNA conformation change

3 of 25

1.62

0.98

0.0092

GO:0090305

Nucleic acid phosphodiester bond hydrolysis

4 of 61

1.36

0.94

0.0061

GO:0090304

Nucleic acid metabolic process

7 of 271

0.95

0.77

0.0017

GO:0006139

Nucleobase-containing compound metabolic process

8 of 441

0.8

0.63

0.0018

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140097

Catalytic activity, acting on DNA

6 of 74

1.45

1.69

2.18e-05

GO:0140657

ATP-dependent activity

6 of 120

1.24

1.27

0.00011

GO:0140640

Catalytic activity, acting on a nucleic acid

7 of 175

1.14

1.19

5.10e-05

GO:0004527

Exonuclease activity

3 of 22

1.68

1.07

0.0063

GO:0008094

ATP-dependent activity, acting on DNA

3 of 23

1.66

1.06

0.0063

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030894

Replisome

2 of 6

2.06

0.85

0.0255

GO:1990391

DNA repair complex

2 of 7

2.0

0.84

0.0255

GO:0043590

Bacterial nucleoid

2 of 16

1.64

0.78

0.0274

GO:0032991

Protein-containing complex

5 of 222

0.89

0.53

0.0255

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:594

Mixed, incl. Homologous recombination, and DNA repair complex

9 of 42

1.87

4.51

2.98e-13

CL:664

Mixed, incl. 5-3 exonuclease, and Helicase and RNase D C-terminal

5 of 5

2.54

4.4

3.00e-09

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-168256

Immune System

3 of 36

1.46

1.08

0.0033

MAP-168249

Innate Immune System

2 of 30

1.37

0.66

0.0389

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0540

Nuclease

3 of 31

1.53

0.84

0.0177

KW-0347

Helicase

3 of 29

1.56

0.84

0.0177

KW-0269

Exonuclease

2 of 14

1.7

0.77

0.0311

KW-0235

DNA replication

2 of 16

1.64

0.76

0.0311

KW-0233

DNA recombination

2 of 15

1.67

0.76

0.0311

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036279

5-3 exonuclease, C-terminal domain superfamily

2 of 2

2.54

0.81

0.0345

IPR020046

5-3 exonuclease, alpha-helical arch, N-terminal

2 of 2

2.54

0.81

0.0345

IPR020045

DNA polymerase I-like, H3TH domain

2 of 2

2.54

0.81

0.0345

IPR008918

Helix-hairpin-helix motif, class 2

2 of 2

2.54

0.81

0.0345

IPR002421

5-3 exonuclease

2 of 2

2.54

0.81

0.0345

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00279

Helix-hairpin-helix class 2 (Pol1 family) motifs

2 of 2

2.54

1.24

0.0054

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (30%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About