STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscUIron-binding protein believed to be involved in Fe-S protein formation or repair; Evidence 2b:Function of strongly homologous gene; Product type pf:putative factor. (138 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase (tRNA sulfurtransferase),PLP-dependent.
 
 0.999
CDI03825.1
Putative DnaJ-like protein DjlA; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.983
CDI02570.1
Cysteine desulfurase.
  
 0.977
sufS
Selenocysteine lyase, PLP-dependent; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 0.977
iscA
Putative regulator believed to be involved in Fe-S cluster assembly and activation; Evidence 3:Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr:putative regulator; Belongs to the HesB/IscA family.
 
  
 0.974
CDI03630.1
Oxidoreductase FAD/NAD(P)-binding domain protein.
  
 0.933
sufC
Component of SufBCD complex, ATP-binding component of ABC superfamily; Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type t:transporter.
  
  
 0.886
erpA
Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG.
 
  
 0.817
iscR
Repressor of the iscRSUA operon, involved in assembly of Fe-S clusters.
 
  
 0.800
dnaK
Chaperone Hsp70 in DNA biosynthesis/cell division; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 
 0.799
Your Current Organism:
Competibacter denitrificans
NCBI taxonomy Id: 1400863
Other names: C. Competibacter denitrificans Run_A_D11, Candidatus Competibacter denitrificans Run_A_D11, Candidatus Competibacter denitrificans strain Run_A_D11
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.