STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HolADNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)    
Predicted Functional Partners:
DnaN
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 
 0.994
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.985
HolB
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.985
OME90848.1
DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.925
polC
PolC-type DNA polymerase III; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
    
 0.918
OME88917.1
DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.918
OME96176.1
Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.866
OME96177.1
RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
       0.701
OME96178.1
Anti-sigma factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.699
OME96047.1
single-stranded-DNA-specific exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.649
Your Current Organism:
Paenibacillus lautus
NCBI taxonomy Id: 1401
Other names: ATCC 43898, Bacillus lautus, CIP 103118, DSM 3035, IFO 15380, JCM 9073, LMG 11157, LMG:11157, NBRC 15380, NRRL NRS-666, P. lautus, Paenibacillus sp. HF_07
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