STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFK64350.1Mevalonate kinase. (318 aa)    
Predicted Functional Partners:
SFK64363.1
Diphosphomevalonate decarboxylase.
 
 
 0.997
SFK82690.1
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 0.997
SFK64380.1
Phosphomevalonate kinase.
 
 
 0.996
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.977
SFK82706.1
hydroxymethylglutaryl-CoA synthase.
 
 
 0.916
SFK96336.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
  0.854
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
    
 0.640
SFK84399.1
Thiolase, C-terminal domain.
  
 0.613
SFK82720.1
acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.613
SFK82752.1
Threonine synthase.
    
  0.467
Your Current Organism:
Trichococcus palustris
NCBI taxonomy Id: 140314
Other names: CIP 105359, DSM 9172, Ruminococcus palustris, Ruminococcus palustris DSM 9172T, T. palustris, strain Z-7189
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.