STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFL16330.1Tartronate-semialdehyde synthase; Belongs to the TPP enzyme family. (560 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
  0.801
SFK91477.1
3-hydroxyisobutyrate dehydrogenase.
  
 
 0.790
ilvD
Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family.
 
     0.770
ilvD-2
Energy-coupling factor transport system ATP-binding protein; Belongs to the IlvD/Edd family.
 
     0.767
SFL16301.1
Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
  0.690
SFL16317.1
Sugar phosphate isomerase/epimerase.
    
  0.647
SFL16350.1
Transcriptional regulator, IclR family.
 
     0.586
SFK63220.1
Chorismate mutase.
  
     0.544
SFL16284.1
Hydroxypyruvate reductase.
     
 0.532
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
     0.497
Your Current Organism:
Trichococcus palustris
NCBI taxonomy Id: 140314
Other names: CIP 105359, DSM 9172, Ruminococcus palustris, Ruminococcus palustris DSM 9172T, T. palustris, strain Z-7189
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