STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (267 aa)    
Predicted Functional Partners:
fadM
Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.922
proC-3
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
  
 
0.915
proA
Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 
 0.913
pruA
Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. RocA subfamily.
   
 0.907
ARJ25077.1
Proline racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the proline racemase family.
    
 0.906
ARJ22463.1
Proline racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the proline racemase family.
    
 0.906
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 
 0.904
ARJ21918.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.900
ARJ23789.1
2OG-Fe(II) oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
yvgN
Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.803
Your Current Organism:
Bacillus mycoides
NCBI taxonomy Id: 1405
Other names: ATCC 6462, B. mycoides, Bacillus sp. B38V, Bacillus sp. CHR3P1B1, Bacillus sp. JP44SK50, Bacillus sp. JP44SK9, Bacillus sp. TAN 119, Bacillus weihenstephanensis, CCUG 26678, CIP 103472, CIP 105772 [[Bacillus weihenstephanensis]], DSM 11821 [[Bacillus weihenstephanensis]], DSM 2048, LMG 18989 [[Bacillus weihenstephanensis]], LMG 7128, LMG:18989 [[Bacillus weihenstephanensis]], LMG:7128, NBRC 101228, NBRC 101238 [[Bacillus weihenstephanensis]], NCTC 12974, NRRL B-14799, NRRL B-14811, NRRL B-23307 [[Bacillus weihenstephanensis]], NRRL NRS-273, WSBC 10204 [[Bacillus weihenstephanensis]]
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