STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topB-2DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (714 aa)    
Predicted Functional Partners:
ARJ21234.1
Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.873
recQ
DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.785
ARJ20281.1
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.637
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.573
ssbB
Single-stranded DNA-binding protein; Binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.542
ssb
Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 0.542
dinG
ATP-dependent helicase DinG; 3'-5' exonuclease.
  
 0.534
ARJ21010.1
ErpL protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.497
ARJ22032.1
Exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.497
secDF
Protein translocase subunit SecDF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.491
Your Current Organism:
Bacillus mycoides
NCBI taxonomy Id: 1405
Other names: ATCC 6462, B. mycoides, Bacillus sp. B38V, Bacillus sp. CHR3P1B1, Bacillus sp. JP44SK50, Bacillus sp. JP44SK9, Bacillus sp. TAN 119, Bacillus weihenstephanensis, CCUG 26678, CIP 103472, CIP 105772 [[Bacillus weihenstephanensis]], DSM 11821 [[Bacillus weihenstephanensis]], DSM 2048, LMG 18989 [[Bacillus weihenstephanensis]], LMG 7128, LMG:18989 [[Bacillus weihenstephanensis]], LMG:7128, NBRC 101228, NBRC 101238 [[Bacillus weihenstephanensis]], NCTC 12974, NRRL B-14799, NRRL B-14811, NRRL B-23307 [[Bacillus weihenstephanensis]], NRRL NRS-273, WSBC 10204 [[Bacillus weihenstephanensis]]
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