arpJ protein (Paenibacillus polymyxa) - STRING interaction network

Nodes:

Network nodes represent proteins

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Coexpression

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[Homology]

Score

arpJ

Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)

Predicted Functional Partners:

glnQ

0.997

glnQ5

0.948

glnQ1

0.944

yckI

0.942

glnQ3

0.942

glnQ7

0.942

hisP

0.940

glnQ11

0.939

glnQ-2

0.937

glnP5

0.773

Your Current Organism:

Paenibacillus polymyxa

NCBI taxonomy Id: 1406
Other names: ATCC 842, Aerobacillus polymyxa, Bacillus polymyxa, Bacillus sp. NCIM 2538, Bacillus sp. NCIM 2540, Bacillus sp. NCIM 2726, Bacillus sp. RP 2.2, CCUG 7426, CFBP 4258, CIP 66.22, Clostridium polymyxa, DSM 36, Granulobacter polymyxa, HAMBI 635, IAM 13419, IFO 15309, JCM 2507, LMG 13294, LMG:13294, NBRC 15309, NCCB 24016, NCIB 8158, NCIB:8158, NCTC 10343, NRRL B-4317, P. polymyxa, Paenibacillus sp. JCM 8035, Paenibacillus sp. JCM 8036, Paenibacillus sp. JCM 8037, Paenibacillus sp. JCM 8038, Paenibacillus sp. JCM 8039, Paenibacillus sp. WLY78, VKM B-514

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
arpJ	glnP5	LK13_01130	LK13_17270	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
arpJ	glnQ	LK13_01130	LK13_01125	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Similar to ATP-binding component of ABC transporters; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
arpJ	glnQ-2	LK13_01130	LK13_12150	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Similar to ATP-binding component of ABC transporters; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.937
arpJ	glnQ1	LK13_01130	LK13_14985	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.944
arpJ	glnQ11	LK13_01130	LK13_11110	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.939
arpJ	glnQ3	LK13_01130	LK13_17100	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.942
arpJ	glnQ5	LK13_01130	LK13_17275	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.948
arpJ	glnQ7	LK13_01130	LK13_17895	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.942
arpJ	hisP	LK13_01130	LK13_23315	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.940
arpJ	yckI	LK13_01130	LK13_05855	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Arginine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.942
glnP5	arpJ	LK13_17270	LK13_01130	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.773
glnP5	glnQ	LK13_17270	LK13_01125	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Similar to ATP-binding component of ABC transporters; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.938
glnP5	glnQ-2	LK13_17270	LK13_12150	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Similar to ATP-binding component of ABC transporters; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
glnP5	glnQ1	LK13_17270	LK13_14985	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.925
glnP5	glnQ11	LK13_17270	LK13_11110	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
glnP5	glnQ3	LK13_17270	LK13_17100	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.930
glnP5	glnQ5	LK13_17270	LK13_17275	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
glnP5	glnQ7	LK13_17270	LK13_17895	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.930
glnP5	hisP	LK13_17270	LK13_23315	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Amino acid ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
glnP5	yckI	LK13_17270	LK13_05855	Glutamine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	Arginine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.925

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

13

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 87

0.85

0.9

3.87e-07

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

10 of 38

1.17

1.65

2.23e-09

GO:0003735

Structural constituent of ribosome

11 of 49

1.1

1.51

6.05e-10

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 50

1.09

1.51

1.92e-10

GO:0044391

Ribosomal subunit

3 of 12

1.14

0.72

0.0141

GO:0015934

Large ribosomal subunit

2 of 6

1.27

0.59

0.0497

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:74

rRNA-binding

10 of 18

1.49

2.89

3.94e-12

CL:71

Structural constituent of ribosome

11 of 31

1.3

2.2

3.94e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

11 of 52

1.07

1.46

2.46e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

10 of 35

1.2

1.75

1.38e-09

GOCC:0044391

Ribosomal subunit

6 of 17

1.29

1.54

8.28e-06

GOCC:0022626

Cytosolic ribosome

5 of 14

1.3

1.37

7.43e-05

GOCC:0015934

Large ribosomal subunit

3 of 6

1.45

1.08

0.0031

GOCC:0043229

Intracellular organelle

11 of 79

0.89

1.01

1.55e-08

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

10 of 37

1.18

1.71

7.93e-10

KW-0689

Ribosomal protein

11 of 51

1.08

1.47

4.02e-10

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