A0A1J7IPG4 protein (Coniochaeta ligniaria) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

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[Homology]

Score

A0A1J7IPG4

Ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family. (202 aa)

Predicted Functional Partners:

A0A1J7I7B6

0.999

A0A1J7I895

0.999

A0A1J7IAH9

0.999

A0A1J7IBI7

0.999

A0A1J7IBZ1

0.999

A0A1J7IEK9

0.999

A0A1J7IF09

0.999

A0A1J7IFU4

0.999

A0A1J7IH50

0.999

A0A1J7IJA2

0.999

Your Current Organism:

Coniochaeta ligniaria

NCBI taxonomy Id: 1408157
Other names: C. ligniaria NRRL 30616, Coniochaeta ligniaria NRRL 30616

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1J7I7B6	A0A1J7I895	Cytosolic large ribosomal subunit protein L30.	60S ribosomal protein L5.	0.999
A0A1J7I7B6	A0A1J7IAH9	Cytosolic large ribosomal subunit protein L30.	L30e-like protein.	0.999
A0A1J7I7B6	A0A1J7IBI7	Cytosolic large ribosomal subunit protein L30.	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.	0.999
A0A1J7I7B6	A0A1J7IBZ1	Cytosolic large ribosomal subunit protein L30.	Uncharacterized protein.	0.998
A0A1J7I7B6	A0A1J7IEK9	Cytosolic large ribosomal subunit protein L30.	Putative 60S ribosomal protein L31.	0.999
A0A1J7I7B6	A0A1J7IF09	Cytosolic large ribosomal subunit protein L30.	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.998
A0A1J7I7B6	A0A1J7IFU4	Cytosolic large ribosomal subunit protein L30.	60S ribosomal protein L20.	0.999
A0A1J7I7B6	A0A1J7IH50	Cytosolic large ribosomal subunit protein L30.	Putative 40S ribosomal protein S20.	0.999
A0A1J7I7B6	A0A1J7IJA2	Cytosolic large ribosomal subunit protein L30.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.998
A0A1J7I7B6	A0A1J7IPG4	Cytosolic large ribosomal subunit protein L30.	Ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	0.999
A0A1J7I895	A0A1J7I7B6	60S ribosomal protein L5.	Cytosolic large ribosomal subunit protein L30.	0.999
A0A1J7I895	A0A1J7IAH9	60S ribosomal protein L5.	L30e-like protein.	0.999
A0A1J7I895	A0A1J7IBI7	60S ribosomal protein L5.	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.	0.999
A0A1J7I895	A0A1J7IBZ1	60S ribosomal protein L5.	Uncharacterized protein.	0.999
A0A1J7I895	A0A1J7IEK9	60S ribosomal protein L5.	Putative 60S ribosomal protein L31.	0.999
A0A1J7I895	A0A1J7IF09	60S ribosomal protein L5.	Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.	0.999
A0A1J7I895	A0A1J7IFU4	60S ribosomal protein L5.	60S ribosomal protein L20.	0.999
A0A1J7I895	A0A1J7IH50	60S ribosomal protein L5.	Putative 40S ribosomal protein S20.	0.999
A0A1J7I895	A0A1J7IJA2	60S ribosomal protein L5.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.998
A0A1J7I895	A0A1J7IPG4	60S ribosomal protein L5.	Ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.	0.999

page 1 of 6

Network Stats

number of nodes:

3

number of edges:

3

average node degree:

2

avg. local clustering coefficient:

1

expected number of edges:

2

PPI enrichment p-value:

0.216

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0007021

Tubulin complex assembly

4 of 9

2.43

2.66

8.92e-06

GO:0015976

Carbon utilization

3 of 6

2.49

1.81

0.00044

GO:0071244

Cellular response to carbon dioxide

2 of 2

2.79

1.06

0.0119

GO:0007023

Post-chaperonin tubulin folding pathway

2 of 3

2.61

1.03

0.0132

GO:0006457

Protein folding

4 of 88

1.44

0.89

0.0109

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004089

Carbonate dehydratase activity

3 of 5

2.56

1.95

0.00025

GO:0015631

Tubulin binding

4 of 37

1.82

1.7

0.00026

GO:0048487

Beta-tubulin binding

2 of 2

2.79

1.2

0.0066

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005874

Microtubule

4 of 35

1.84

1.75

0.00021

GO:0015630

Microtubule cytoskeleton

5 of 94

1.51

1.5

0.00021

GO:0099080

Supramolecular complex

5 of 117

1.42

1.41

0.00021

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9794

Tubulin complex assembly, and Alpha-tubulin binding

6 of 10

2.56

5.36

3.12e-11

CL:9799

Beta-tubulin binding, and CAP Gly-rich domain

5 of 5

2.79

4.97

4.45e-10

CL:5291

Mixed, incl. Carbonate dehydratase activity, and Atypical dual-specificity phosphatase Siw14-like

3 of 26

1.85

1.25

0.0032

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00910

Nitrogen metabolism

3 of 12

2.18

1.91

0.00020

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-391251

Protein folding

4 of 24

2.01

2.05

6.85e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036874

Carbonic anhydrase superfamily

2 of 2

2.79

0.82

0.0332

IPR001765

Carbonic anhydrase

2 of 2

2.79

0.82

0.0332

IPR036859

CAP Gly-rich domain superfamily

2 of 4

2.49

0.81

0.0332

IPR000938

CAP Gly-rich domain

2 of 4

2.49

0.81

0.0332

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00947

Carbonic anhydrase

2 of 2

2.79

1.34

0.0037

SM01052

Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including ...

2 of 4

2.49

1.27

0.0046

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