STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1J7IY00Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1087 aa)    
Predicted Functional Partners:
A0A1J7IR82
Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
    
 0.999
A0A1J7J2C2
TYR_PHOSPHATASE_2 domain-containing protein.
    
 0.997
A0A1J7IFD6
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.996
A0A1J7INM0
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.996
A0A1J7J5B7
DNA-directed RNA polymerase II 19 kDa polypeptide.
    
 0.996
A0A1J7JC60
Insert subdomain of RNA polymerase alpha subunit.
    
 0.996
A0A1J7JXD8
DNA-directed RNA polymerases II 24 kDa polypeptide.
    
 0.996
A0A1J7JUD2
RNA polymerase Rpb6.
    
 0.995
A0A1J7IQN1
RBP11-like subunits of RNA polymerase.
    
 0.993
A0A1J7IY99
Metallothionein-I gene transcription activator.
    
 0.993
Your Current Organism:
Coniochaeta ligniaria
NCBI taxonomy Id: 1408157
Other names: C. ligniaria NRRL 30616, Coniochaeta ligniaria NRRL 30616
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