A0A1J7IZI7 protein (Coniochaeta ligniaria) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

A0A1J7IZI7

Uncharacterized protein. (396 aa)

Predicted Functional Partners:

A0A1J7JAF0

0.856

A0A1J7IXZ4

0.797

A0A1J7J5T2

0.771

A0A1J7JTY2

0.769

A0A1J7IBS3

0.737

A0A1J7JRA6

0.717

A0A1J7IT19

0.707

A0A1J7JN66

0.707

A0A1J7IJ87

0.701

A0A1J7J3G6

0.701

Your Current Organism:

Coniochaeta ligniaria

NCBI taxonomy Id: 1408157
Other names: C. ligniaria NRRL 30616, Coniochaeta ligniaria NRRL 30616

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1J7IBS3	A0A1J7IT19	Tr-type G domain-containing protein.	Ski2_N domain-containing protein.	0.867
A0A1J7IBS3	A0A1J7IZI7	Tr-type G domain-containing protein.	Uncharacterized protein.	0.737
A0A1J7IBS3	A0A1J7JAF0	Tr-type G domain-containing protein.	TPR-like protein.	0.889
A0A1J7IBS3	A0A1J7JN66	Tr-type G domain-containing protein.	DSHCT domain-containing protein.	0.867
A0A1J7IJ87	A0A1J7IZI7	SMN domain-containing protein.	Uncharacterized protein.	0.701
A0A1J7IT19	A0A1J7IBS3	Ski2_N domain-containing protein.	Tr-type G domain-containing protein.	0.867
A0A1J7IT19	A0A1J7IZI7	Ski2_N domain-containing protein.	Uncharacterized protein.	0.707
A0A1J7IT19	A0A1J7JAF0	Ski2_N domain-containing protein.	TPR-like protein.	0.987
A0A1J7IXZ4	A0A1J7IZI7	CDC73-domain-containing protein.	Uncharacterized protein.	0.797
A0A1J7IXZ4	A0A1J7J3G6	CDC73-domain-containing protein.	Cullin-domain-containing protein; Belongs to the cullin family.	0.604
A0A1J7IXZ4	A0A1J7J5T2	CDC73-domain-containing protein.	Uncharacterized protein.	0.999
A0A1J7IXZ4	A0A1J7JRA6	CDC73-domain-containing protein.	CPSF_A domain-containing protein.	0.699
A0A1J7IXZ4	A0A1J7JTY2	CDC73-domain-containing protein.	Tetratricopeptide repeat protein 1.	0.999
A0A1J7IZI7	A0A1J7IBS3	Uncharacterized protein.	Tr-type G domain-containing protein.	0.737
A0A1J7IZI7	A0A1J7IJ87	Uncharacterized protein.	SMN domain-containing protein.	0.701
A0A1J7IZI7	A0A1J7IT19	Uncharacterized protein.	Ski2_N domain-containing protein.	0.707
A0A1J7IZI7	A0A1J7IXZ4	Uncharacterized protein.	CDC73-domain-containing protein.	0.797
A0A1J7IZI7	A0A1J7J3G6	Uncharacterized protein.	Cullin-domain-containing protein; Belongs to the cullin family.	0.701
A0A1J7IZI7	A0A1J7J5T2	Uncharacterized protein.	Uncharacterized protein.	0.771
A0A1J7IZI7	A0A1J7JAF0	Uncharacterized protein.	TPR-like protein.	0.856

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

13

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006457

Protein folding

5 of 10

2.12

2.93

8.73e-07

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005515

Protein binding

6 of 26

1.78

2.68

3.10e-07

GO:0140662

ATP-dependent protein folding chaperone

3 of 4

2.29

1.77

0.00044

GO:0051082

Unfolded protein binding

3 of 6

2.12

1.69

0.00052

GO:0140657

ATP-dependent activity

5 of 115

1.05

0.77

0.0053

GO:0030554

Adenyl nucleotide binding

6 of 310

0.7

0.4

0.0482

(more ...)

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:34828326

(2021) Effect of High Hydrostatic Pressure on Stress-Related dnaK, hrcA, and ctsR Expression Patterns in Selected Lactobacilli Strains.

6 of 6

2.42

5.42

8.62e-12

PMID:34526534

(2021) Evaluation of probiotic characteristics and whole genome analysis of Pediococcus pentosaceus MR001 for use as probiotic bacteria in shrimp aquaculture.

2 of 4

2.12

1.46

0.0016

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:496

Chaperone, and HSP20-like chaperone

11 of 19

2.18

7.75

1.28e-20

CL:499

Protein folding, and C-terminal, D2-small domain, of ClpB protein

8 of 11

2.28

6.16

2.31e-14

CL:503

Protein folding

6 of 6

2.42

4.98

8.73e-11

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1236975

Antigen processing-Cross presentation

2 of 2

2.42

1.47

0.0019

MAP-983169

Class I MHC mediated antigen processing & presentation

2 of 5

2.02

1.28

0.0033

MAP-1280218

Adaptive Immune System

2 of 5

2.02

1.28

0.0033

MAP-168256

Immune System

2 of 25

1.32

0.7

0.0266

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0143

Chaperone

6 of 14

2.05

3.76

4.09e-09

KW-0346

Stress response

4 of 8

2.12

2.6

5.16e-06

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00011

Hsp20/alpha crystallin family

2 of 2

2.42

0.81

0.0337

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