node1 | node2 | node1 annotation | node2 annotation | score |
A0A1J7IBW3 | A0A1J7IYZ5 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Uridine kinase; Belongs to the uridine kinase family. | 0.698 |
A0A1J7IBW3 | A0A1J7J366 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.849 |
A0A1J7IBW3 | A0A1J7J5W3 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. | 0.873 |
A0A1J7IBW3 | A0A1J7JCE7 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Deoxyribose-phosphate aldolase. | 0.655 |
A0A1J7IBW3 | A0A1J7JQ55 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Uracil phosphoribosyltransferase. | 0.698 |
A0A1J7IBW3 | A0A1J7K038 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Inosine/uridine-preferring nucleoside hydrolase. | 0.806 |
A0A1J7IF05 | A0A1J7IPE4 | Glyceraldehyde-3-phosphate dehydrogenase. | Bifunctional dihydrofolate reductase-thymidylate synthase. | 0.463 |
A0A1J7IF05 | A0A1J7IYZ5 | Glyceraldehyde-3-phosphate dehydrogenase. | Uridine kinase; Belongs to the uridine kinase family. | 0.889 |
A0A1J7IF05 | A0A1J7J366 | Glyceraldehyde-3-phosphate dehydrogenase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.896 |
A0A1J7IF05 | A0A1J7J5W3 | Glyceraldehyde-3-phosphate dehydrogenase. | Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins. Belongs to the phosphohexose mutase family. | 0.911 |
A0A1J7IF05 | A0A1J7JCE7 | Glyceraldehyde-3-phosphate dehydrogenase. | Deoxyribose-phosphate aldolase. | 0.896 |
A0A1J7IF05 | A0A1J7JQ55 | Glyceraldehyde-3-phosphate dehydrogenase. | Uracil phosphoribosyltransferase. | 0.889 |
A0A1J7IPE4 | A0A1J7IF05 | Bifunctional dihydrofolate reductase-thymidylate synthase. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.463 |
A0A1J7IPE4 | A0A1J7IR45 | Bifunctional dihydrofolate reductase-thymidylate synthase. | Uncharacterized protein. | 0.902 |
A0A1J7IPE4 | A0A1J7IRM6 | Bifunctional dihydrofolate reductase-thymidylate synthase. | Thymidylate_kin domain-containing protein. | 0.908 |
A0A1J7IPE4 | A0A1J7IYZ5 | Bifunctional dihydrofolate reductase-thymidylate synthase. | Uridine kinase; Belongs to the uridine kinase family. | 0.426 |
A0A1J7IPE4 | A0A1J7J366 | Bifunctional dihydrofolate reductase-thymidylate synthase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.899 |
A0A1J7IPE4 | A0A1J7JCE7 | Bifunctional dihydrofolate reductase-thymidylate synthase. | Deoxyribose-phosphate aldolase. | 0.507 |
A0A1J7IPE4 | A0A1J7JQ55 | Bifunctional dihydrofolate reductase-thymidylate synthase. | Uracil phosphoribosyltransferase. | 0.426 |
A0A1J7IR45 | A0A1J7IPE4 | Uncharacterized protein. | Bifunctional dihydrofolate reductase-thymidylate synthase. | 0.902 |