node1 | node2 | node1 annotation | node2 annotation | score |
A0A1J7IKN1 | A0A1J7IXW5 | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.804 |
A0A1J7IKN1 | A0A1J7IYH9 | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.811 |
A0A1J7IKN1 | A0A1J7J667 | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.812 |
A0A1J7IKN1 | A0A1J7J8U9 | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.920 |
A0A1J7IKN1 | A0A1J7JK90 | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.993 |
A0A1J7IKN1 | A0A1J7JP57 | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | Cytochrome P450; Belongs to the cytochrome P450 family. | 0.793 |
A0A1J7IKN1 | A0A1J7JPW5 | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | Squalene epoxidase. | 0.793 |
A0A1J7IXW5 | A0A1J7IKN1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | 0.804 |
A0A1J7IXW5 | A0A1J7J8U9 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.969 |
A0A1J7IXW5 | A0A1J7JK90 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.811 |
A0A1J7IXW5 | A0A1J7JP57 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Cytochrome P450; Belongs to the cytochrome P450 family. | 0.850 |
A0A1J7IXW5 | A0A1J7JPW5 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Squalene epoxidase. | 0.836 |
A0A1J7IYH9 | A0A1J7IKN1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | 0.811 |
A0A1J7IYH9 | A0A1J7J8U9 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.970 |
A0A1J7IYH9 | A0A1J7JK90 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.811 |
A0A1J7IYH9 | A0A1J7JP57 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Cytochrome P450; Belongs to the cytochrome P450 family. | 0.850 |
A0A1J7IYH9 | A0A1J7JPW5 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Squalene epoxidase. | 0.836 |
A0A1J7J667 | A0A1J7IKN1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. | 0.812 |
A0A1J7J667 | A0A1J7J8U9 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 3-hydroxy-3-methylglutaryl coenzyme A reductase. | 0.970 |
A0A1J7J667 | A0A1J7JK90 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.811 |