STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1J7J8U93-hydroxy-3-methylglutaryl coenzyme A reductase. (1184 aa)    
Predicted Functional Partners:
A0A1J7IYH9
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.970
A0A1J7J667
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.970
A0A1J7IXW5
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 
 0.969
A0A1J7JK90
Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
  
 0.934
A0A1J7JPW5
Squalene epoxidase.
   
  
 0.928
A0A1J7IKN1
Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family.
  
 
 0.920
A0A1J7JP57
Cytochrome P450; Belongs to the cytochrome P450 family.
   
  
 0.915
A0A1J7K0N1
Uncharacterized protein.
   
 
 0.911
A0A1J7J867
RING-type domain-containing protein.
   
 
 0.895
A0A1J7JAE9
Uncharacterized protein.
   
 
 0.866
Your Current Organism:
Coniochaeta ligniaria
NCBI taxonomy Id: 1408157
Other names: C. ligniaria NRRL 30616, Coniochaeta ligniaria NRRL 30616
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