A0A1J7JAB1 protein (Coniochaeta ligniaria) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

A0A1J7JAB1

Uncharacterized protein. (284 aa)

Predicted Functional Partners:

A0A1J7IUB3

0.639

A0A1J7IJQ5

0.614

A0A1J7JDZ3

0.594

A0A1J7IJF9

0.578

A0A1J7J8E9

0.578

A0A1J7JGN0

0.578

A0A1J7ILG2

0.570

A0A1J7J461

0.570

A0A1J7JEC6

0.570

A0A1J7ING1

0.559

Your Current Organism:

Coniochaeta ligniaria

NCBI taxonomy Id: 1408157
Other names: C. ligniaria NRRL 30616, Coniochaeta ligniaria NRRL 30616

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1J7IJF9	A0A1J7IJQ5	GDPD-domain-containing protein.	GP-PDE domain-containing protein.	0.948
A0A1J7IJF9	A0A1J7ILG2	GDPD-domain-containing protein.	Cullin-domain-containing protein; Belongs to the cullin family.	0.593
A0A1J7IJF9	A0A1J7ING1	GDPD-domain-containing protein.	Sumo conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.597
A0A1J7IJF9	A0A1J7IUB3	GDPD-domain-containing protein.	Uncharacterized protein.	0.753
A0A1J7IJF9	A0A1J7J461	GDPD-domain-containing protein.	Cullin-domain-containing protein; Belongs to the cullin family.	0.593
A0A1J7IJF9	A0A1J7J8E9	GDPD-domain-containing protein.	GDPD-domain-containing protein.	0.944
A0A1J7IJF9	A0A1J7JAB1	GDPD-domain-containing protein.	Uncharacterized protein.	0.578
A0A1J7IJF9	A0A1J7JDZ3	GDPD-domain-containing protein.	Serine/threonine-protein phosphatase.	0.753
A0A1J7IJF9	A0A1J7JEC6	GDPD-domain-containing protein.	BRCT domain-containing protein.	0.570
A0A1J7IJF9	A0A1J7JGN0	GDPD-domain-containing protein.	Rho-type GTPase-activating protein.	0.578
A0A1J7IJQ5	A0A1J7IJF9	GP-PDE domain-containing protein.	GDPD-domain-containing protein.	0.948
A0A1J7IJQ5	A0A1J7ILG2	GP-PDE domain-containing protein.	Cullin-domain-containing protein; Belongs to the cullin family.	0.590
A0A1J7IJQ5	A0A1J7ING1	GP-PDE domain-containing protein.	Sumo conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.593
A0A1J7IJQ5	A0A1J7IUB3	GP-PDE domain-containing protein.	Uncharacterized protein.	0.733
A0A1J7IJQ5	A0A1J7J461	GP-PDE domain-containing protein.	Cullin-domain-containing protein; Belongs to the cullin family.	0.590
A0A1J7IJQ5	A0A1J7J8E9	GP-PDE domain-containing protein.	GDPD-domain-containing protein.	0.948
A0A1J7IJQ5	A0A1J7JAB1	GP-PDE domain-containing protein.	Uncharacterized protein.	0.614
A0A1J7IJQ5	A0A1J7JDZ3	GP-PDE domain-containing protein.	Serine/threonine-protein phosphatase.	0.781
A0A1J7IJQ5	A0A1J7JEC6	GP-PDE domain-containing protein.	BRCT domain-containing protein.	0.570
A0A1J7IJQ5	A0A1J7JGN0	GP-PDE domain-containing protein.	Rho-type GTPase-activating protein.	0.578

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.701

expected number of edges:

10

PPI enrichment p-value:

7.98e-11

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006352

DNA-templated transcription, initiation

11 of 24

2.26

8.41

1.92e-21

GO:0050896

Response to stimulus

11 of 334

1.11

1.61

2.89e-11

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016987

Sigma factor activity

11 of 24

2.26

8.48

1.09e-21

GO:0003677

DNA binding

11 of 369

1.07

1.45

3.36e-10

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1196

0.56

0.49

8.24e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6080

RNA polymerase sigma-70 like, and Sigma factor antagonist activity

10 of 35

2.05

6.17

5.00e-17

CL:6082

RNA polymerase sigma-70 like, and Sigma factor antagonist activity

8 of 28

2.05

5.1

3.69e-13

CL:6084

RNA polymerase sigma-70 like, and FecR protein

7 of 22

2.1

4.7

1.65e-11

CL:6109

Sigma-70, region 4

4 of 6

2.42

3.18

7.33e-07

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

11 of 478

0.96

1.16

4.17e-09

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

11 of 55

1.9

5.74

1.17e-18

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0731

Sigma factor

11 of 22

2.3

8.94

1.53e-22

KW-0238

DNA-binding

11 of 178

1.39

2.67

4.04e-14

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04542

Sigma-70 region 2

10 of 19

2.32

8.05

2.09e-19

PF08281

Sigma-70, region 4

8 of 13

2.39

6.76

3.32e-15

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007627

RNA polymerase sigma-70 region 2

11 of 20

2.34

9.0

4.97e-22

IPR039425

RNA polymerase sigma-70 like

11 of 21

2.32

8.89

4.97e-22

IPR014284

RNA polymerase sigma-70 like domain

11 of 22

2.3

8.78

4.97e-22

IPR013325

RNA polymerase sigma factor, region 2

11 of 22

2.3

8.78

4.97e-22

IPR013324

RNA polymerase sigma factor, region 3/4-like

11 of 22

2.3

8.78

4.97e-22

(more ...)

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