A0A1J7K0H2 protein (Coniochaeta ligniaria) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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A0A1J7K0H2

Putative quinone oxidoreductase. (347 aa)

Predicted Functional Partners:

A0A1J7J5D6

0.718

A0A1J7JSW8

0.718

A0A1J7IY82

0.576

A0A1J7J8Y1

0.563

A0A1J7JCE7

0.492

A0A1J7II45

0.471

A0A1J7I4S7

0.469

A0A1J7I531

0.469

A0A1J7IAV3

0.469

A0A1J7IB84

0.469

Your Current Organism:

Coniochaeta ligniaria

NCBI taxonomy Id: 1408157
Other names: C. ligniaria NRRL 30616, Coniochaeta ligniaria NRRL 30616

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1J7I4S7	A0A1J7J8Y1	Thiolase-like protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.	Ketoacyl-synt-domain-containing protein.	0.602
A0A1J7I4S7	A0A1J7K0H2	Thiolase-like protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.	Putative quinone oxidoreductase.	0.469
A0A1J7I531	A0A1J7J8Y1	Beta-ketoacyl synthase domain-containing protein.	Ketoacyl-synt-domain-containing protein.	0.662
A0A1J7I531	A0A1J7K0H2	Beta-ketoacyl synthase domain-containing protein.	Putative quinone oxidoreductase.	0.469
A0A1J7IAV3	A0A1J7J8Y1	Thiolase-like protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.	Ketoacyl-synt-domain-containing protein.	0.602
A0A1J7IAV3	A0A1J7K0H2	Thiolase-like protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.	Putative quinone oxidoreductase.	0.469
A0A1J7IB84	A0A1J7J8Y1	Putative polyketide synthase.	Ketoacyl-synt-domain-containing protein.	0.656
A0A1J7IB84	A0A1J7K0H2	Putative polyketide synthase.	Putative quinone oxidoreductase.	0.469
A0A1J7II45	A0A1J7K0H2	4-hydroxyphenylpyruvate dioxygenase.	Putative quinone oxidoreductase.	0.471
A0A1J7IY82	A0A1J7J5D6	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Cytochrome b5 heme-binding domain-containing protein.	0.919
A0A1J7IY82	A0A1J7JSW8	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Molybdopterin binding oxidoreductase.	0.919
A0A1J7IY82	A0A1J7K0H2	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	Putative quinone oxidoreductase.	0.576
A0A1J7J5D6	A0A1J7IY82	Cytochrome b5 heme-binding domain-containing protein.	Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.	0.919
A0A1J7J5D6	A0A1J7JSW8	Cytochrome b5 heme-binding domain-containing protein.	Molybdopterin binding oxidoreductase.	0.828
A0A1J7J5D6	A0A1J7K0H2	Cytochrome b5 heme-binding domain-containing protein.	Putative quinone oxidoreductase.	0.718
A0A1J7J8Y1	A0A1J7I4S7	Ketoacyl-synt-domain-containing protein.	Thiolase-like protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.	0.602
A0A1J7J8Y1	A0A1J7I531	Ketoacyl-synt-domain-containing protein.	Beta-ketoacyl synthase domain-containing protein.	0.662
A0A1J7J8Y1	A0A1J7IAV3	Ketoacyl-synt-domain-containing protein.	Thiolase-like protein; Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.	0.602
A0A1J7J8Y1	A0A1J7IB84	Ketoacyl-synt-domain-containing protein.	Putative polyketide synthase.	0.656
A0A1J7J8Y1	A0A1J7K0H2	Ketoacyl-synt-domain-containing protein.	Putative quinone oxidoreductase.	0.563

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

47

average node degree:

8.55

avg. local clustering coefficient:

0.828

expected number of edges:

11

PPI enrichment p-value:

2.89e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022900

Electron transport chain

11 of 79

1.72

4.39

3.26e-16

GO:0006119

Oxidative phosphorylation

7 of 30

1.94

4.07

9.72e-11

GO:0019646

Aerobic electron transport chain

4 of 12

2.1

2.69

3.11e-06

GO:0022904

Respiratory electron transport chain

5 of 32

1.77

2.47

1.30e-06

GO:0042773

ATP synthesis coupled electron transport

2 of 12

1.8

0.77

0.0322

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004129

Cytochrome-c oxidase activity

10 of 23

2.21

7.32

1.65e-18

GO:0016682

Oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor

4 of 9

2.22

3.04

8.05e-07

GO:0005507

Copper ion binding

4 of 11

2.14

2.87

1.36e-06

GO:0009486

Cytochrome bo3 ubiquinol oxidase activity

3 of 3

2.58

2.68

9.92e-06

GO:0020037

Heme binding

3 of 28

1.61

1.24

0.0020

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070469

Respirasome

6 of 16

2.15

4.24

5.93e-10

GO:0005886

Plasma membrane

11 of 792

0.72

0.71

8.24e-07

GO:0016021

Integral component of membrane

11 of 885

0.67

0.64

1.39e-06

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3024

Cytochrome-c oxidase activity, and Cytochrome C oxidase subunit IV, prokaryotes

11 of 19

2.34

9.08

2.90e-22

CL:3026

Mixed, incl. Copper, and Heme O metabolic process

4 of 7

2.33

3.09

9.14e-07

CL:3045

Oxidoreductase activity, acting on diphenols and related substances as donors, and Heme O metabolic process

2 of 5

2.18

1.02

0.0124

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00190

Oxidative phosphorylation

11 of 88

1.67

4.22

1.02e-16

map01100

Metabolic pathways

11 of 1467

0.45

0.38

0.00072

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0070469

Respirasome

8 of 40

1.88

4.18

7.86e-12

GOCC:0009319

Cytochrome o ubiquinol oxidase complex

2 of 5

2.18

1.02

0.0126

GOCC:0016020

Membrane

11 of 677

0.79

0.81

3.39e-07

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0679

Respiratory chain

6 of 11

2.31

4.71

1.75e-10

KW-0560

Oxidoreductase

8 of 154

1.29

1.83

4.93e-08

KW-0186

Copper

2 of 3

2.4

1.48

0.0018

KW-1133

Transmembrane helix

11 of 985

0.62

0.57

7.89e-06

KW-0812

Transmembrane

11 of 985

0.62

0.57

7.89e-06

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00510

Cytochrome c oxidase subunit III

4 of 4

2.58

3.16

1.11e-06

PF00116

Cytochrome C oxidase subunit II, periplasmic domain

4 of 6

2.4

3.0

1.66e-06

PF02790

Cytochrome C oxidase subunit II, transmembrane domain

2 of 2

2.58

1.16

0.0076

PF00115

Cytochrome C and Quinol oxidase polypeptide I

2 of 7

2.03

0.78

0.0341

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR024791

Cytochrome c oxidase subunit III

4 of 4

2.58

2.96

2.81e-06

IPR011759

Cytochrome C oxidase subunit II, transmembrane domain

4 of 4

2.58

2.96

2.81e-06

IPR035973

Cytochrome c oxidase subunit III-like superfamily

4 of 5

2.48

2.92

2.81e-06

IPR000298

Cytochrome c oxidase subunit III-like

4 of 5

2.48

2.92

2.81e-06

IPR045187

Cytochrome c/quinol oxidase subunit II

4 of 6

2.4

2.89

2.81e-06

(more ...)

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