STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1J7K113Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)    
Predicted Functional Partners:
A0A1J7IHB2
Histone H2B; Belongs to the histone H2B family.
 
 0.998
A0A1J7J7Y0
Histone H3; Belongs to the histone H3 family.
 
 
 0.986
A0A1J7IDW9
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
  
0.964
A0A1J7IWW4
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
  
0.964
A0A1J7J2Z0
Histone H3-like centromeric protein cse-4.
 
 
 0.943
A0A1J7IZ78
Histone H2A; Belongs to the histone H2A family.
 
 
 0.939
A0A1J7IXC0
Uncharacterized protein.
    
 0.935
A0A1J7JC13
Histone H2A; Belongs to the histone H2A family.
 
 
 0.927
A0A1J7IR77
BRCT domain-containing protein.
    
 0.906
A0A1J7JC60
Insert subdomain of RNA polymerase alpha subunit.
    
 0.905
Your Current Organism:
Coniochaeta ligniaria
NCBI taxonomy Id: 1408157
Other names: C. ligniaria NRRL 30616, Coniochaeta ligniaria NRRL 30616
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.