T310_10227 protein (Rasamsonia emersonii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

T310_10227

DAO domain-containing protein. (178 aa)

Predicted Functional Partners:

T310_3526

0.782

T310_7395

0.759

T310_3990

0.688

T310_3175

0.688

T310_8065

0.686

T310_7479

0.686

T310_4699

0.686

T310_3715

0.686

T310_2646

0.686

T310_1277

0.686

Your Current Organism:

Rasamsonia emersonii

NCBI taxonomy Id: 1408163
Other names: R. emersonii CBS 393.64, Rasamsonia emersonii CBS 393.64, Rasamsonia emersonii CBS393.64

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T310_10227	T310_1277	A0A0F4YEZ7	A0A0F4Z2F9	DAO domain-containing protein.	Thioredoxin reductase GliT-like protein.	0.686
T310_10227	T310_2646	A0A0F4YEZ7	A0A0F4YYC2	DAO domain-containing protein.	Nitrite reductase (NAD(P)H).	0.686
T310_10227	T310_3175	A0A0F4YEZ7	A0A0F4YXI4	DAO domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.688
T310_10227	T310_3526	A0A0F4YEZ7	A0A0F4YVW6	DAO domain-containing protein.	Neutral amino acid permease.	0.782
T310_10227	T310_3715	A0A0F4YEZ7	A0A0F4YW17	DAO domain-containing protein.	AMID-like mitochondrial oxidoreductase.	0.686
T310_10227	T310_3990	A0A0F4YEZ7	A0A0F4YUR9	DAO domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.688
T310_10227	T310_4699	A0A0F4YEZ7	A0A0F4YUG1	DAO domain-containing protein.	Pyridine nucleotide-disulfide oxidoreductase-like protein.	0.686
T310_10227	T310_7395	A0A0F4YEZ7	A0A0F4YKM2	DAO domain-containing protein.	Serine--pyruvate transaminase.	0.759
T310_10227	T310_7479	A0A0F4YEZ7	A0A0F4YLS9	DAO domain-containing protein.	Monodehydroascorbate reductase (NADH).	0.686
T310_10227	T310_8065	A0A0F4YEZ7	A0A0F4YJD1	DAO domain-containing protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.686
T310_1277	T310_10227	A0A0F4Z2F9	A0A0F4YEZ7	Thioredoxin reductase GliT-like protein.	DAO domain-containing protein.	0.686
T310_1277	T310_3175	A0A0F4Z2F9	A0A0F4YXI4	Thioredoxin reductase GliT-like protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.667
T310_1277	T310_3526	A0A0F4Z2F9	A0A0F4YVW6	Thioredoxin reductase GliT-like protein.	Neutral amino acid permease.	0.661
T310_1277	T310_3990	A0A0F4Z2F9	A0A0F4YUR9	Thioredoxin reductase GliT-like protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.667
T310_1277	T310_7395	A0A0F4Z2F9	A0A0F4YKM2	Thioredoxin reductase GliT-like protein.	Serine--pyruvate transaminase.	0.509
T310_2646	T310_10227	A0A0F4YYC2	A0A0F4YEZ7	Nitrite reductase (NAD(P)H).	DAO domain-containing protein.	0.686
T310_2646	T310_3175	A0A0F4YYC2	A0A0F4YXI4	Nitrite reductase (NAD(P)H).	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.667
T310_2646	T310_3526	A0A0F4YYC2	A0A0F4YVW6	Nitrite reductase (NAD(P)H).	Neutral amino acid permease.	0.661
T310_2646	T310_3990	A0A0F4YYC2	A0A0F4YUR9	Nitrite reductase (NAD(P)H).	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.667
T310_2646	T310_7395	A0A0F4YYC2	A0A0F4YKM2	Nitrite reductase (NAD(P)H).	Serine--pyruvate transaminase.	0.509

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.813

expected number of edges:

19

PPI enrichment p-value:

0.0261

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009084

Glutamine family amino acid biosynthetic process

6 of 28

1.86

2.96

1.05e-07

GO:0006561

Proline biosynthetic process

4 of 5

2.43

2.95

2.25e-06

GO:0009064

Glutamine family amino acid metabolic process

7 of 51

1.67

2.67

6.20e-08

GO:0055129

L-proline biosynthetic process

2 of 2

2.53

1.37

0.0030

GO:1901566

Organonitrogen compound biosynthetic process

10 of 479

0.85

0.86

3.45e-06

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1495

Mixed, incl. Glutamate metabolic process, and Oxidoreductase FAD/NAD(P)-binding

5 of 29

1.77

2.1

1.67e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00330

Arginine and proline metabolism

4 of 42

1.51

1.33

0.00073

map00332

Carbapenem biosynthesis

2 of 3

2.35

1.32

0.0035

map00250

Alanine, aspartate and glutamate metabolism

3 of 33

1.49

1.09

0.0035

map01230

Biosynthesis of amino acids

5 of 164

1.02

0.77

0.0035

map01110

Biosynthesis of secondary metabolites

7 of 428

0.74

0.56

0.0035

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0641

Proline biosynthesis

3 of 3

2.53

2.19

8.17e-05

KW-0028

Amino-acid biosynthesis

4 of 68

1.3

0.96

0.0041

KW-0963

Cytoplasm

6 of 258

0.9

0.67

0.0041

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About