T310_7859 protein (Rasamsonia emersonii) - STRING interaction network

Nodes:

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white nodes:
second shell of interactors

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filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

T310_7859

Uncharacterized protein. (275 aa)

Predicted Functional Partners:

T310_3459

0.999

T310_7312

0.998

T310_6074

0.998

T310_5183

0.998

T310_4939

0.998

T310_1560

0.998

T310_5177

0.997

T310_4808

0.997

T310_0299

0.996

T310_2065

0.988

Your Current Organism:

Rasamsonia emersonii

NCBI taxonomy Id: 1408163
Other names: R. emersonii CBS 393.64, Rasamsonia emersonii CBS 393.64, Rasamsonia emersonii CBS393.64

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T310_0299	T310_1560	A0A0F4Z560	A0A0F4Z1Z5	RNase_PH domain-containing protein.	Uncharacterized protein.	0.996
T310_0299	T310_2065	A0A0F4Z560	A0A0F4Z1D8	RNase_PH domain-containing protein.	ATP dependent RNA helicase (Dob1).	0.967
T310_0299	T310_3459	A0A0F4Z560	A0A0F4YXE1	RNase_PH domain-containing protein.	Exosomal 3'-5' exoribonuclease complex.	0.997
T310_0299	T310_4808	A0A0F4Z560	A0A0F4YSU5	RNase_PH domain-containing protein.	Exosome complex endonuclease 2/ribosomal RNA processing protein.	0.996
T310_0299	T310_4939	A0A0F4Z560	A0A0F4YTR8	RNase_PH domain-containing protein.	Exosome complex endonuclease 1.	0.995
T310_0299	T310_5177	A0A0F4Z560	A0A0F4YRD8	RNase_PH domain-containing protein.	Exosome complex exonuclease exoribonuclease (Rrp44); Belongs to the RNR ribonuclease family.	0.994
T310_0299	T310_5183	A0A0F4Z560	A0A0F4YT16	RNase_PH domain-containing protein.	RNase_PH domain-containing protein.	0.998
T310_0299	T310_6074	A0A0F4Z560	A0A0F4YNU2	RNase_PH domain-containing protein.	3'-5' exoribonuclease.	0.997
T310_0299	T310_7312	A0A0F4Z560	A0A0F4YKD6	RNase_PH domain-containing protein.	3' exoribonuclease family protein.	0.997
T310_0299	T310_7859	A0A0F4Z560	A0A0F4YK11	RNase_PH domain-containing protein.	Uncharacterized protein.	0.996
T310_1560	T310_0299	A0A0F4Z1Z5	A0A0F4Z560	Uncharacterized protein.	RNase_PH domain-containing protein.	0.996
T310_1560	T310_2065	A0A0F4Z1Z5	A0A0F4Z1D8	Uncharacterized protein.	ATP dependent RNA helicase (Dob1).	0.995
T310_1560	T310_3459	A0A0F4Z1Z5	A0A0F4YXE1	Uncharacterized protein.	Exosomal 3'-5' exoribonuclease complex.	0.998
T310_1560	T310_4808	A0A0F4Z1Z5	A0A0F4YSU5	Uncharacterized protein.	Exosome complex endonuclease 2/ribosomal RNA processing protein.	0.997
T310_1560	T310_4939	A0A0F4Z1Z5	A0A0F4YTR8	Uncharacterized protein.	Exosome complex endonuclease 1.	0.998
T310_1560	T310_5177	A0A0F4Z1Z5	A0A0F4YRD8	Uncharacterized protein.	Exosome complex exonuclease exoribonuclease (Rrp44); Belongs to the RNR ribonuclease family.	0.994
T310_1560	T310_5183	A0A0F4Z1Z5	A0A0F4YT16	Uncharacterized protein.	RNase_PH domain-containing protein.	0.998
T310_1560	T310_6074	A0A0F4Z1Z5	A0A0F4YNU2	Uncharacterized protein.	3'-5' exoribonuclease.	0.996
T310_1560	T310_7312	A0A0F4Z1Z5	A0A0F4YKD6	Uncharacterized protein.	3' exoribonuclease family protein.	0.997
T310_1560	T310_7859	A0A0F4Z1Z5	A0A0F4YK11	Uncharacterized protein.	Uncharacterized protein.	0.998

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Network Stats

number of nodes:

11

number of edges:

42

average node degree:

7.64

avg. local clustering coefficient:

0.922

expected number of edges:

10

PPI enrichment p-value:

1.04e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006644

Phospholipid metabolic process

6 of 125

1.74

2.42

1.48e-06

GO:0008654

Phospholipid biosynthetic process

5 of 95

1.78

2.21

8.94e-06

GO:0006650

Glycerophospholipid metabolic process

5 of 97

1.77

2.2

8.94e-06

GO:0006629

Lipid metabolic process

7 of 291

1.44

1.91

1.74e-06

GO:0046474

Glycerophospholipid biosynthetic process

4 of 76

1.78

1.79

0.00013

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016780

Phosphotransferase activity, for other substituted phosphate groups

2 of 11

2.32

0.9

0.0223

GO:0042578

Phosphoric ester hydrolase activity

4 of 174

1.42

0.89

0.0103

GO:0003824

Catalytic activity

10 of 3163

0.56

0.4

0.0103

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:15229

Inositol phosphate metabolism

3 of 12

2.46

1.84

0.00038

CL:9328

Mixed, incl. Glycerophospholipid catabolic process, and Cell cycle G1/S phase transition

3 of 13

2.42

1.83

0.00038

CL:13210

Phospholipid metabolism, and Phosphatidylserine decarboxylase

2 of 6

2.58

1.31

0.0041

CL:9330

Mixed, incl. Cell cycle G1/S phase transition, and SPX domain

2 of 7

2.52

1.27

0.0047

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00564

Glycerophospholipid metabolism

5 of 76

1.88

2.74

5.88e-07

map00562

Inositol phosphate metabolism

3 of 43

1.9

1.62

0.00050

map00030

Pentose phosphate pathway

2 of 21

2.04

1.16

0.0060

map04070

Phosphatidylinositol signaling system

2 of 48

1.68

0.82

0.0228

map01100

Metabolic pathways

8 of 1691

0.74

0.61

0.00054

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1855183

Synthesis of IP2, IP, and Ins in the cytosol

2 of 5

2.66

1.12

0.0093

MAP-71336

Pentose phosphate pathway

2 of 14

2.22

0.87

0.0242

MAP-1483249

Inositol phosphate metabolism

2 of 16

2.16

0.87

0.0242

MAP-71387

Metabolism of carbohydrates

3 of 137

1.4

0.68

0.0362

MAP-1430728

Metabolism

7 of 1121

0.86

0.59

0.0093

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0460

Magnesium

3 of 46

1.88

1.36

0.0019

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00459

Inositol monophosphatase family

2 of 2

3.06

1.34

0.0038

PF01066

CDP-alcohol phosphatidyltransferase

2 of 5

2.66

1.2

0.0066

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR020583

Inositol monophosphatase, metal-binding site

2 of 2

3.06

1.08

0.0112

IPR020550

Inositol monophosphatase, conserved site

2 of 2

3.06

1.08

0.0112

IPR000760

Inositol monophosphatase-like

2 of 2

3.06

1.08

0.0112

IPR043130

CDP-alcohol phosphatidyltransferase, transmembrane domain

2 of 5

2.66

1.07

0.0112

IPR000462

CDP-alcohol phosphatidyltransferase

2 of 5

2.66

1.07

0.0112

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