T310_6967 protein (Rasamsonia emersonii) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

T310_6967

Long-chain-acyl-CoA dehydrogenase. (540 aa)

Predicted Functional Partners:

T310_1142

0.914

T310_3328

0.878

T310_7301

0.870

T310_0345

0.852

T310_1270

0.849

T310_5054

0.834

T310_10260

0.812

T310_8080

0.803

T310_0611

0.801

T310_3925

0.794

Your Current Organism:

Rasamsonia emersonii

NCBI taxonomy Id: 1408163
Other names: R. emersonii CBS 393.64, Rasamsonia emersonii CBS 393.64, Rasamsonia emersonii CBS393.64

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T310_0345	T310_0611	A0A0F4Z693	A0A0F4Z671	Propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.895
T310_0345	T310_10260	A0A0F4Z693	A0A0F4YEW2	Propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Short chain dehydrogenase.	0.905
T310_0345	T310_3328	A0A0F4Z693	A0A0F4YXV2	Propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Electron transfer flavoprotein alpha subunit.	0.766
T310_0345	T310_3925	A0A0F4Z693	A0A0F4YV97	Propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyryl-CoA dehydrogenase.	0.846
T310_0345	T310_6967	A0A0F4Z693	A0A0F4YMI7	Propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Long-chain-acyl-CoA dehydrogenase.	0.852
T310_0345	T310_7301	A0A0F4Z693	A0A0F4YKF0	Propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Electron transfer flavoprotein, beta subunit.	0.603
T310_0611	T310_0345	A0A0F4Z671	A0A0F4Z693	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.895
T310_0611	T310_10260	A0A0F4Z671	A0A0F4YEW2	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Short chain dehydrogenase.	0.845
T310_0611	T310_1270	A0A0F4Z671	A0A0F4Z3R8	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	NADH:ubiquinone reductase (H(+)-translocating); Belongs to the complex I 49 kDa subunit family.	0.427
T310_0611	T310_3328	A0A0F4Z671	A0A0F4YXV2	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Electron transfer flavoprotein alpha subunit.	0.887
T310_0611	T310_3925	A0A0F4Z671	A0A0F4YV97	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	3-hydroxybutyryl-CoA dehydrogenase.	0.995
T310_0611	T310_6967	A0A0F4Z671	A0A0F4YMI7	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Long-chain-acyl-CoA dehydrogenase.	0.801
T310_0611	T310_7301	A0A0F4Z671	A0A0F4YKF0	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	Electron transfer flavoprotein, beta subunit.	0.899
T310_10260	T310_0345	A0A0F4YEW2	A0A0F4Z693	Short chain dehydrogenase.	Propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.905
T310_10260	T310_0611	A0A0F4YEW2	A0A0F4Z671	Short chain dehydrogenase.	Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.845
T310_10260	T310_1270	A0A0F4YEW2	A0A0F4Z3R8	Short chain dehydrogenase.	NADH:ubiquinone reductase (H(+)-translocating); Belongs to the complex I 49 kDa subunit family.	0.525
T310_10260	T310_3328	A0A0F4YEW2	A0A0F4YXV2	Short chain dehydrogenase.	Electron transfer flavoprotein alpha subunit.	0.816
T310_10260	T310_3925	A0A0F4YEW2	A0A0F4YV97	Short chain dehydrogenase.	3-hydroxybutyryl-CoA dehydrogenase.	0.859
T310_10260	T310_5054	A0A0F4YEW2	A0A0F4YRP1	Short chain dehydrogenase.	NADH-ubiquinone oxidoreductase subunit; Belongs to the complex I 30 kDa subunit family.	0.404
T310_10260	T310_6967	A0A0F4YEW2	A0A0F4YMI7	Short chain dehydrogenase.	Long-chain-acyl-CoA dehydrogenase.	0.812

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Network Stats

number of nodes:

3

number of edges:

2

average node degree:

1.33

avg. local clustering coefficient:

0.667

expected number of edges:

2

PPI enrichment p-value:

0.532

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006633

Fatty acid biosynthetic process

6 of 23

1.74

2.48

9.20e-07

GO:0019752

Carboxylic acid metabolic process

7 of 225

0.82

0.65

0.0018

GO:0071704

Organic substance metabolic process

11 of 1099

0.32

0.26

0.0194

GO:0044238

Primary metabolic process

10 of 910

0.36

0.26

0.0410

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004312

Fatty acid synthase activity

6 of 14

1.96

3.24

4.28e-08

GO:0004315

3-oxoacyl-[acyl-carrier-protein] synthase activity

4 of 10

1.93

2.07

4.75e-05

GO:0033818

Beta-ketoacyl-acyl-carrier-protein synthase III activity

3 of 4

2.2

1.84

0.00029

GO:0016616

Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

4 of 27

1.49

1.32

0.00072

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 776

0.47

0.4

0.00061

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:767

Fatty acid biosynthesis

7 of 13

2.05

4.24

1.81e-10

CL:770

Beta-ketoacyl synthase, active site, and KR domain

4 of 6

2.15

2.71

3.26e-06

CL:643

Carbon metabolism, and Valine, leucine and isoleucine degradation

8 of 106

1.2

1.54

3.98e-07

CL:783

acetyl-CoA carboxylase complex, and Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal

2 of 5

1.93

0.87

0.0220

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00061

Fatty acid biosynthesis

9 of 28

1.83

4.42

1.36e-13

map01212

Fatty acid metabolism

9 of 36

1.72

3.89

4.80e-13

map00780

Biotin metabolism

4 of 20

1.62

1.7

0.00010

map01100

Metabolic pathways

11 of 845

0.44

0.37

0.00044

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0444

Lipid biosynthesis

4 of 21

1.6

1.43

0.00059

KW-0275

Fatty acid biosynthesis

3 of 11

1.76

1.33

0.0017

KW-0511

Multifunctional enzyme

2 of 5

1.93

0.95

0.0153

KW-0012

Acyltransferase

3 of 32

1.3

0.78

0.0153

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF08545

3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III

3 of 4

2.2

1.58

0.0010

PF08541

3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal

3 of 4

2.2

1.58

0.0010

PF08659

KR domain

3 of 8

1.9

1.4

0.0016

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR002347

Short-chain dehydrogenase/reductase SDR

4 of 10

1.93

1.76

0.00026

IPR013751

Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal

3 of 3

2.32

1.75

0.00051

IPR016039

Thiolase-like

4 of 13

1.81

1.67

0.00030

IPR013747

Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal

3 of 4

2.2

1.67

0.00066

IPR036291

NAD(P)-binding domain superfamily

5 of 62

1.23

1.03

0.0013

(more ...)

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