STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
T310_6698Ubiquitin--protein ligase. (1225 aa)    
Predicted Functional Partners:
T310_8009
Uncharacterized protein.
   
 
 0.831
T310_6697
50S ribosomal protein YmL27.
 
      0.800
T310_3384
Proteasome endopeptidase complex.
    
 
 0.770
T310_1178
Ubiquitin--protein ligase; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.761
T310_5155
26S proteasome regulatory subunit RPN1; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
    
 
 0.642
T310_1268
NEDD8 activating enzyme (UbaC).
   
 
 0.616
T310_3622
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
     
 0.595
T310_4481
Pathway: involved in N-terminal ubiquitin fusion degradation proteolytic pathway.
   
 
 0.592
T310_5799
RING zinc finger protein.
   
 0.579
T310_1086
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.563
Your Current Organism:
Rasamsonia emersonii
NCBI taxonomy Id: 1408163
Other names: R. emersonii CBS 393.64, Rasamsonia emersonii CBS 393.64, Rasamsonia emersonii CBS393.64
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.