T310_2380 protein (Rasamsonia emersonii) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

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[Homology]

Score

T310_2380

Ribose-phosphate pyrophosphokinase. (693 aa)

Predicted Functional Partners:

T310_2249

0.966

T310_0471

0.923

T310_5442

0.922

T310_1397

0.920

T310_1877

0.914

T310_1463

0.903

T310_7455

0.892

T310_10101

0.886

T310_5462

0.886

T310_9682

0.881

Your Current Organism:

Rasamsonia emersonii

NCBI taxonomy Id: 1408163
Other names: R. emersonii CBS 393.64, Rasamsonia emersonii CBS 393.64, Rasamsonia emersonii CBS393.64

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T310_0471	T310_10101	A0A0F4Z4S4	A0A0F4YDR8	Phosphoglucomutase.	ADP-ribose diphosphatase; Belongs to the Nudix hydrolase family.	0.887
T310_0471	T310_1397	A0A0F4Z4S4	A0A0F4Z3T9	Phosphoglucomutase.	Amidophosphoribosyltransferase.	0.607
T310_0471	T310_1877	A0A0F4Z4S4	A0A0F4Z117	Phosphoglucomutase.	Ribose-5-phosphate isomerase.	0.917
T310_0471	T310_2249	A0A0F4Z4S4	A0A0F4YZQ2	Phosphoglucomutase.	Ribose-phosphate diphosphokinase.	0.923
T310_0471	T310_2380	A0A0F4Z4S4	A0A0F4Z146	Phosphoglucomutase.	Ribose-phosphate pyrophosphokinase.	0.923
T310_0471	T310_5442	A0A0F4Z4S4	A0A0F4YRR6	Phosphoglucomutase.	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.	0.909
T310_0471	T310_5462	A0A0F4Z4S4	A0A0F4YSA5	Phosphoglucomutase.	Ribose-phosphate diphosphokinase.	0.923
T310_0471	T310_7455	A0A0F4Z4S4	A0A0F4YL52	Phosphoglucomutase.	Phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.963
T310_10101	T310_0471	A0A0F4YDR8	A0A0F4Z4S4	ADP-ribose diphosphatase; Belongs to the Nudix hydrolase family.	Phosphoglucomutase.	0.887
T310_10101	T310_1397	A0A0F4YDR8	A0A0F4Z3T9	ADP-ribose diphosphatase; Belongs to the Nudix hydrolase family.	Amidophosphoribosyltransferase.	0.641
T310_10101	T310_2249	A0A0F4YDR8	A0A0F4YZQ2	ADP-ribose diphosphatase; Belongs to the Nudix hydrolase family.	Ribose-phosphate diphosphokinase.	0.886
T310_10101	T310_2380	A0A0F4YDR8	A0A0F4Z146	ADP-ribose diphosphatase; Belongs to the Nudix hydrolase family.	Ribose-phosphate pyrophosphokinase.	0.886
T310_10101	T310_5462	A0A0F4YDR8	A0A0F4YSA5	ADP-ribose diphosphatase; Belongs to the Nudix hydrolase family.	Ribose-phosphate diphosphokinase.	0.886
T310_10101	T310_7455	A0A0F4YDR8	A0A0F4YL52	ADP-ribose diphosphatase; Belongs to the Nudix hydrolase family.	Phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.883
T310_1397	T310_0471	A0A0F4Z3T9	A0A0F4Z4S4	Amidophosphoribosyltransferase.	Phosphoglucomutase.	0.607
T310_1397	T310_10101	A0A0F4Z3T9	A0A0F4YDR8	Amidophosphoribosyltransferase.	ADP-ribose diphosphatase; Belongs to the Nudix hydrolase family.	0.641
T310_1397	T310_1463	A0A0F4Z3T9	A0A0F4Z1P8	Amidophosphoribosyltransferase.	Orotate phosphoribosyltransferase.	0.523
T310_1397	T310_2249	A0A0F4Z3T9	A0A0F4YZQ2	Amidophosphoribosyltransferase.	Ribose-phosphate diphosphokinase.	0.920
T310_1397	T310_2380	A0A0F4Z3T9	A0A0F4Z146	Amidophosphoribosyltransferase.	Ribose-phosphate pyrophosphokinase.	0.920
T310_1397	T310_5462	A0A0F4Z3T9	A0A0F4YSA5	Amidophosphoribosyltransferase.	Ribose-phosphate diphosphokinase.	0.920

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

18

average node degree:

3.27

avg. local clustering coefficient:

0.898

expected number of edges:

13

PPI enrichment p-value:

0.0888

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006352

DNA-templated transcription, initiation

9 of 46

1.92

4.77

1.31e-13

GO:0050896

Response to stimulus

9 of 308

1.1

1.4

4.91e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016987

Sigma factor activity

9 of 46

1.92

4.83

7.61e-14

GO:0140110

Transcription regulator activity

11 of 162

1.46

2.95

7.61e-14

GO:0003677

DNA binding

9 of 372

1.01

1.15

1.11e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

9 of 1163

0.52

0.36

0.0138

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5963

FecR protein, and RNA polymerase sigma-70, Bacteroidetes type

11 of 42

2.05

6.79

1.23e-19

CL:5970

FecR protein, and RNA polymerase sigma-70, Bacteroidetes type

9 of 25

2.19

6.62

1.32e-16

CL:5973

FecR protein, and RNA polymerase sigma-70, Bacteroidetes type

7 of 17

2.24

5.45

1.12e-12

CL:5974

FecR protein, and RNA polymerase sigma-70 region 4

5 of 11

2.29

3.94

9.48e-09

CL:5986

RNA polymerase sigma-70 region 4, and FecR protein

3 of 5

2.41

2.3

4.42e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02020

Two-component system

11 of 459

1.01

1.29

1.05e-09

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000428

DNA-directed RNA polymerase complex

9 of 76

1.7

3.71

2.14e-12

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0731

Sigma factor

9 of 43

1.95

5.13

1.33e-14

KW-0238

DNA-binding

9 of 192

1.3

2.03

1.05e-09

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04542

Sigma-70 region 2

9 of 42

1.96

5.07

3.49e-14

PF08281

Sigma-70, region 4

4 of 24

1.85

1.87

0.00011

PF04545

Sigma-70, region 4

3 of 16

1.9

1.36

0.0020

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR007627

RNA polymerase sigma-70 region 2

9 of 40

1.98

5.09

5.76e-14

IPR039425

RNA polymerase sigma-70 like

9 of 41

1.97

5.05

5.76e-14

IPR014327

RNA polymerase sigma-70, Bacteroidetes type

7 of 20

2.17

4.99

7.64e-12

IPR013325

RNA polymerase sigma factor, region 2

9 of 43

1.95

4.97

5.76e-14

IPR014284

RNA polymerase sigma-70 like domain

9 of 44

1.94

4.94

5.76e-14

(more ...)

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