STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
KOH46905.1TIGRFAM: ilvE_II: branched-chain amino acid aminotransferase; Pfam: Aminotransferase class IV. (343 aa)    
Predicted Functional Partners:
ilvD-2
TIGRFAM: ilvD: dihydroxy-acid dehydratase; Pfam: Dehydratase family; Belongs to the IlvD/Edd family.
  
 0.963
ilvD
Pfam: Dehydratase family; TIGRFAM: ilvD: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.937
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 0.933
KOH44224.1
Aspartokinase; Pfam: Homoserine dehydrogenase; Pfam: ACT domain; TIGRFAM: asp_kinases: aspartate kinase; Pfam: Amino acid kinase family; Pfam: Homoserine dehydrogenase, NAD binding domain.
  
 
 0.895
KOH45470.1
TIGRFAM: pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase; Pfam: Domain of unknown function; Pfam: 4Fe-4S dicluster domain; Pfam: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; SMART: Domain of unknown function; Pfam: Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg; Pfam: Pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.892
KOH46313.1
2-oxoisovalerate dehydrogenase subunit beta; Pfam: Transketolase, C-terminal domain; Pfam: Dehydrogenase E1 component; SMART: Transketolase, pyrimidine binding domain; Pfam: Transketolase, pyrimidine binding domain.
  
 0.882
KOH46784.1
Transketolase; Pfam: Dehydrogenase E1 component; Pfam: Transketolase, C-terminal domain; Pfam: Transketolase, pyrimidine binding domain; SMART: Transketolase, pyrimidine binding domain.
  
 0.877
KOH46133.1
Pfam: Dehydrogenase E1 component; SMART: Transketolase, pyrimidine binding domain; Pfam: Transketolase, C-terminal domain; Pfam: Transketolase, pyrimidine binding domain.
  
 0.871
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     
 0.843
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.808
Your Current Organism:
Sunxiuqinia dokdonensis
NCBI taxonomy Id: 1409788
Other names: CGMCC 1.12676, JCM 19380, KCTC 32503, S. dokdonensis, Sunxiuqinia sp. DH1, strain DH1
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