STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (393 aa)    
Predicted Functional Partners:
KOH46409.1
Pfam: Indole-3-glycerol phosphate synthase.
 
 0.999
trpF
Pfam: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family.
 
 0.999
trpA
Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.994
KOH46407.1
PRINTS: Anthranilate synthase component II signature; Pfam: Glutamine amidotransferase class-I; PRINTS: Glutamine amidotransferase superfamily signature; PRINTS: Carbamoyl-phosphate synthase protein GATase domain signature; TIGRFAM: trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase.
 
 
 0.991
KOH46406.1
Pfam: Anthranilate synthase component I, N terminal region; Pfam: chorismate binding enzyme; PRINTS: Anthranilate synthase component I signature.
 
  
 0.977
KOH42741.1
Para-aminobenzoate synthase; Pfam: chorismate binding enzyme; PRINTS: Anthranilate synthase component I signature.
 
  
 0.931
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.854
KOH44224.1
Aspartokinase; Pfam: Homoserine dehydrogenase; Pfam: ACT domain; TIGRFAM: asp_kinases: aspartate kinase; Pfam: Amino acid kinase family; Pfam: Homoserine dehydrogenase, NAD binding domain.
  
 
 0.844
KOH46154.1
Hypothetical protein; Pfam: Pyridoxal-phosphate dependent enzyme.
  
 0.835
Your Current Organism:
Sunxiuqinia dokdonensis
NCBI taxonomy Id: 1409788
Other names: CGMCC 1.12676, JCM 19380, KCTC 32503, S. dokdonensis, Sunxiuqinia sp. DH1, strain DH1
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