STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOH45776.1Pfam: Hsp90 protein; PRINTS: 90kDa heat shock protein signature; Pfam: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (683 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.998
KOH45148.1
Pfam: DnaJ domain; SMART: DnaJ molecular chaperone homology domain; Pfam: Tellurite resistance protein TerB; PRINTS: DnaJ domain signature.
  
 0.986
KOH43365.1
Histidine kinase; Pfam: Tetratricopeptide repeat; SMART: Histidine kinase-like ATPases; PRINTS: Bacterial sensor protein C-terminal signature; Pfam: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Pfam: His Kinase A (phospho-acceptor) domain; SMART: Tetratricopeptide repeats; SMART: His Kinase A (phosphoacceptor) domain.
   
 0.986
KOH42705.1
Histidine kinase; Pfam: Tetratricopeptide repeat; Pfam: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; SMART: Histidine kinase-like ATPases; SMART: Tetratricopeptide repeats; SMART: His Kinase A (phosphoacceptor) domain; PRINTS: Bacterial sensor protein C-terminal signature; Pfam: His Kinase A (phospho-acceptor) domain.
   
 0.986
KOH42658.1
Pfam: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; SMART: His Kinase A (phosphoacceptor) domain; PRINTS: Bacterial sensor protein C-terminal signature; SMART: Histidine kinase-like ATPases; Pfam: Tetratricopeptide repeat; SMART: Tetratricopeptide repeats; Pfam: His Kinase A (phospho-acceptor) domain.
   
 0.986
KOH45562.1
Hypothetical protein; Pfam: DnaJ domain; SMART: DnaJ molecular chaperone homology domain; Pfam: DnaJ C terminal domain; PRINTS: DnaJ domain signature.
  
 0.985
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 0.985
KOH43153.1
ATPase; Pfam: Activator of Hsp90 ATPase homolog 1-like protein.
   
 
 0.966
KOH45107.1
Hypothetical protein; Pfam: Leucine rich repeat; SMART: Leucine-rich repeats, typical (most populated) subfamily.
  
 0.962
guaB
Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.945
Your Current Organism:
Sunxiuqinia dokdonensis
NCBI taxonomy Id: 1409788
Other names: CGMCC 1.12676, JCM 19380, KCTC 32503, S. dokdonensis, Sunxiuqinia sp. DH1, strain DH1
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