STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (363 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
 0.999
gcvH
Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 0.999
KOH44456.1
Pfam: Glycine cleavage H-protein.
 
 0.999
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 0.996
KOH45411.1
Hypothetical protein; Pfam: FAD dependent oxidoreductase.
  
 0.972
folD
Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.926
KOH46131.1
Pyridine nucleotide-disulfide oxidoreductase; PRINTS: Pyridine nucleotide disulphide reductase class-I signature; Pfam: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: lipoamide_DH: dihydrolipoyl dehydrogenase; PRINTS: FAD-dependent pyridine nucleotide reductase signature; Pfam: Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
 
 0.911
KOH44347.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.911
KOH46959.1
Glutamate synthase; Pfam: GXGXG motif; Pfam: Conserved region in glutamate synthase; Pfam: Glutamine amidotransferases class-II; Pfam: Glutamate synthase central domain.
  
 
 0.903
KOH45947.1
Hypothetical protein.
   
 0.893
Your Current Organism:
Sunxiuqinia dokdonensis
NCBI taxonomy Id: 1409788
Other names: CGMCC 1.12676, JCM 19380, KCTC 32503, S. dokdonensis, Sunxiuqinia sp. DH1, strain DH1
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