STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rrp41Exosome complex exonuclease 1; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (245 aa)    
Predicted Functional Partners:
rrp4
KH domain protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
 
 0.999
rrp42
3' exoribonuclease family, domain 1; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.
 
0.999
csl4
Exosome complex exonuclease RRP4 N-terminal region; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
  
 0.999
dnaG
Toprim domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
 
 0.933
T478_0403
rRNA metabolism protein, SBDS family.
 
  
 0.909
T478_0368
KH domain protein.
  
  0.908
nep1
EMG1/NEP1 methyltransferase; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
   
 0.901
rpsD
Ribosomal protein S4.
 
  0.890
T478_1082
snoRNA-binding domain protein.
   
  0.878
rps6e
Ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 
  0.862
Your Current Organism:
Nitrosopelagicus brevis
NCBI taxonomy Id: 1410606
Other names: C. Nitrosopelagicus brevis, Candidatus Nitrosopelagicus brevis, ammonia-oxidizing marine archaeon V2
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