STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESS10434.1Putative pyrophosphatase. (115 aa)    
Predicted Functional Partners:
ESS10435.1
Hypothetical protein.
 
     0.932
hisE
phosphoribosyl-ATP pyrophosphatase.
     
 0.757
ESS11119.1
Thymidylate synthase.
    
  0.688
ESS12675.1
Adenine/guanine phosphoribosyltransferase.
    
  0.676
ESS12110.1
Adenine/guanine phosphoribosyltransferase.
    
  0.676
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
    
  0.647
guaAB
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
  0.647
ESS12902.1
Hypothetical protein.
    
  0.640
ESS11545.1
Putative hydrolase of HD superfamily.
  
  
  0.607
ESS11857.1
GMP synthase - glutamine amidotransferase domain protein.
    
  0.577
Your Current Organism:
uncultured archaeon A07HR60
NCBI taxonomy Id: 1412874
Other names: u. archaeon A07HR60
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.