STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CQD18935.1methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (163 aa)    
Predicted Functional Partners:
CQD18932.1
AraC family transcriptional regulator.
 
 
 0.972
CQD19223.1
T/U mismatch-specific DNA glycosylase.
 
  
 0.683
CQD11504.1
RNA polymerase sigma factor SigB; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
   0.648
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
   0.648
CQD19465.1
AraC family transcriptional regulator.
 
 
 0.580
CQD18926.1
Glyoxalase/bleomycin resistance protein/dioxygenase.
       0.550
CQD18929.1
Hypothetical protein.
       0.542
tagA
DNA-3-methyladenine glycosylase I TagA.
   
 0.533
mutT2
7,8-dihydro-8-oxoguanine-triphosphatase; Belongs to the Nudix hydrolase family.
     
 0.508
nucS
Nuclease of the RecB family protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family.
     
 0.451
Your Current Organism:
Mycobacterium lentiflavum
NCBI taxonomy Id: 141349
Other names: ATCC 51985, CCUG 42422, CCUG 42559, CIP 105465, DSM 44418, JCM 13390, M. lentiflavum, strain 2186/92
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