STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB-3Transcriptional regulator; Belongs to the sirtuin family. Class III subfamily. (242 aa)    
Predicted Functional Partners:
CQD08473.1
ATP-dependent DNA helicase II uvrD2.
  
 
 0.966
nadE
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.923
nadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.901
pncA
Pyrazinamidase/nicotinamidas.
  
 0.897
nudC
NADH pyrophosphatase.
    
 0.894
ppnK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.891
CQD03756.1
Alanine dehydrogenase/pyridine nucleotide transhydrogenase.
    
 0.882
pntAB
Pyridine transhydrogenase subunit alpha2.
    
 0.882
deoD
Inosine phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.882
CQD11491.1
Soluble pyridine nucleotide transhydrogenase.
   
 0.882
Your Current Organism:
Mycobacterium lentiflavum
NCBI taxonomy Id: 141349
Other names: ATCC 51985, CCUG 42422, CCUG 42559, CIP 105465, DSM 44418, JCM 13390, M. lentiflavum, strain 2186/92
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