node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CQD17000.1 | cobM | BN1232_03715 | BN1232_03347 | Modulator of DNA gyrase. | Precorrin-4 C11-methyltransferase, CobM; Belongs to the precorrin methyltransferase family. | 0.800 |
CQD17000.1 | egtB | BN1232_03715 | BN1232_05499 | Modulator of DNA gyrase. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.803 |
CQD17000.1 | end | BN1232_03715 | BN1232_01097 | Modulator of DNA gyrase. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.800 |
CQD17000.1 | lpdA_2 | BN1232_03715 | BN1232_01377 | Modulator of DNA gyrase. | Flavoprotein disulfide reductase. | 0.801 |
CQD17000.1 | pyrF | BN1232_03715 | BN1232_02416 | Modulator of DNA gyrase. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.803 |
CQD19897.1 | egtB | BN1232_04709 | BN1232_05499 | Glutamine amidotransferase, class-II. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.824 |
CQD19897.1 | egtC | BN1232_04709 | BN1232_05498 | Glutamine amidotransferase, class-II. | Glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.793 |
CQD19897.1 | egtD | BN1232_04709 | BN1232_05497 | Glutamine amidotransferase, class-II. | Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.742 |
CQD19897.1 | egtE | BN1232_04709 | BN1232_05496 | Glutamine amidotransferase, class-II. | Pyridoxal-phosphate-dependent transferase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.472 |
cobM | CQD17000.1 | BN1232_03347 | BN1232_03715 | Precorrin-4 C11-methyltransferase, CobM; Belongs to the precorrin methyltransferase family. | Modulator of DNA gyrase. | 0.800 |
cobM | egtB | BN1232_03347 | BN1232_05499 | Precorrin-4 C11-methyltransferase, CobM; Belongs to the precorrin methyltransferase family. | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | 0.801 |
cobM | end | BN1232_03347 | BN1232_01097 | Precorrin-4 C11-methyltransferase, CobM; Belongs to the precorrin methyltransferase family. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.802 |
cobM | lpdA_2 | BN1232_03347 | BN1232_01377 | Precorrin-4 C11-methyltransferase, CobM; Belongs to the precorrin methyltransferase family. | Flavoprotein disulfide reductase. | 0.802 |
cobM | pyrF | BN1232_03347 | BN1232_02416 | Precorrin-4 C11-methyltransferase, CobM; Belongs to the precorrin methyltransferase family. | Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.802 |
egtB | CQD17000.1 | BN1232_05499 | BN1232_03715 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Modulator of DNA gyrase. | 0.803 |
egtB | CQD19897.1 | BN1232_05499 | BN1232_04709 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamine amidotransferase, class-II. | 0.824 |
egtB | cobM | BN1232_05499 | BN1232_03347 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Precorrin-4 C11-methyltransferase, CobM; Belongs to the precorrin methyltransferase family. | 0.801 |
egtB | egtC | BN1232_05499 | BN1232_05498 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Glutamine amidotransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. | 0.999 |
egtB | egtD | BN1232_05499 | BN1232_05497 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. | 0.999 |
egtB | egtE | BN1232_05499 | BN1232_05496 | Sulfatase-modifying factor 1; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. | Pyridoxal-phosphate-dependent transferase; Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily. | 0.973 |