STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KOU60688.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)    
Predicted Functional Partners:
KOU60925.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.825
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.727
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
 
 0.680
KOU61215.1
Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.680
KOU60690.1
cobalt-precorrin-6X reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.665
KOU62369.1
2,5-diketo-D-gluconic acid reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.650
KOU77929.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.603
KOU55889.1
Aldo/keto reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.603
KOU60689.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.598
deoD
Purine nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.552
Your Current Organism:
Streptomyces sp. MMG1533
NCBI taxonomy Id: 1415546
Other names: S. sp. MMG1533
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