STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hflXGTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (443 aa)    
Predicted Functional Partners:
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 
 0.976
rpmF
Large subunit ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
    
 
 0.965
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
   
   0.962
SEJ38269.1
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
 
 0.962
rplD
LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
    
 
 0.962
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
    
   0.961
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
    
 
 0.961
rpmA
LSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family.
    
   0.960
rplQ
Large subunit ribosomal protein L17.
    
   0.960
rpmG
LSU ribosomal protein L33P; Belongs to the bacterial ribosomal protein bL33 family.
    
   0.960
Your Current Organism:
Cyclobacterium halophilum
NCBI taxonomy Id: 1416801
Other names: C. halophilum, CECT 8341, Cyclobacterium halophilum Shahinpei et al. 2014, Cyclobacterium sp. GASx41, Cyclobacterium sp. IBRC-M 10761, IBRC-M 10761, strain GASx41
Server load: low (28%) [HD]