STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM26460.1Long-chain acyl-CoA synthetase. (604 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.877
rplE
LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.858
rplR
Large subunit ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
    
 
 0.779
SHL20606.1
PAS domain S-box-containing protein.
    
 0.770
SHL87771.1
PAS domain S-box-containing protein.
    
 0.770
SHM26435.1
2TM domain-containing protein.
       0.703
SHM00319.1
Signal transduction histidine kinase.
  
 
 0.690
SHL18990.1
Acyl-CoA dehydrogenase.
 
 0.657
SHL40102.1
Acyl dehydratase.
  
 
 0.644
SHM84205.1
Hypothetical protein.
  
 0.630
Your Current Organism:
Chitinophaga jiangningensis
NCBI taxonomy Id: 1419482
Other names: C. jiangningensis, CCTCC AB 2013166, Chitinophaga jiangningensis Wang et al. 2014, DSM 27406, JCM 19354, strain JN53
Server load: low (20%) [HD]