STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OQK16749.15'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine. (247 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
 
 0.967
OQK17536.1
N-ethylammeline chlorohydrolase; Catalyzes the hydrolytic cleavage of a carbon-halogen bond in N-ethylammeline; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.963
mtnA
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
 
 0.959
OQK16750.1
Hypoxanthine-guanine phosphoribosyltransferase; Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.901
OQK16748.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.760
OQK16818.1
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 
      0.698
OQK17919.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.642
OQK18612.1
2OG-Fe(II) oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.641
OQK15121.1
Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
  
 
 0.632
OQK18526.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IUNH family.
  
 0.618
Your Current Organism:
Methyloprofundus sedimenti
NCBI taxonomy Id: 1420851
Other names: ATCC BAA-2619, LMG 28393, LMG:28393, M. sedimenti, Methylococcaceae bacterium WF1, Methyloprofundus sedimenti Tavormina et al. 2015, strain WF1
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