V494_05593 protein (Pseudogymnoascus sp. VKMF4513)

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Score

V494_05593

DNA_mis_repair domain-containing protein. (817 aa)

Predicted Functional Partners:

V494_07420

0.988

V494_03584

0.969

V494_02095

0.947

V494_08528

0.935

V494_06535

0.935

V494_03841

0.926

V494_03025

0.894

V494_00106

0.876

V494_03383

0.834

FEN1

0.778

Your Current Organism:

Pseudogymnoascus sp. VKMF4513

NCBI taxonomy Id: 1420907
Other names: P. sp. VKM F-4513 (FW-928), Pseudogymnoascus sp. VKM F-4513 (FW-928)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FEN1	V494_02095	A0A094E2R7	A0A094BMT3	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Fungal_trans domain-containing protein.	0.887
FEN1	V494_03025	A0A094E2R7	A0A094C1T4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.879
FEN1	V494_03383	A0A094E2R7	A0A094BM26	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.999
FEN1	V494_03584	A0A094E2R7	A0A094BF28	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.916
FEN1	V494_03841	A0A094E2R7	A0A094BDS0	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.828
FEN1	V494_05593	A0A094E2R7	A0A094BKC4	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA_mis_repair domain-containing protein.	0.778
FEN1	V494_06535	A0A094E2R7	A0A094AZ72	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.743
FEN1	V494_07420	A0A094E2R7	A0A094DFR7	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	Uncharacterized protein.	0.843
FEN1	V494_08528	A0A094E2R7	A0A094AQR1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.845
V494_00106	V494_05593	A0A094EJ70	A0A094BKC4	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	DNA_mis_repair domain-containing protein.	0.876
V494_00106	V494_07420	A0A094EJ70	A0A094DFR7	Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.	Uncharacterized protein.	0.953
V494_02095	FEN1	A0A094BMT3	A0A094E2R7	Fungal_trans domain-containing protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.887
V494_02095	V494_03025	A0A094BMT3	A0A094C1T4	Fungal_trans domain-containing protein.	Uncharacterized protein.	0.973
V494_02095	V494_03383	A0A094BMT3	A0A094BM26	Fungal_trans domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.998
V494_02095	V494_03584	A0A094BMT3	A0A094BF28	Fungal_trans domain-containing protein.	DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.983
V494_02095	V494_03841	A0A094BMT3	A0A094BDS0	Fungal_trans domain-containing protein.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.983
V494_02095	V494_05593	A0A094BMT3	A0A094BKC4	Fungal_trans domain-containing protein.	DNA_mis_repair domain-containing protein.	0.947
V494_02095	V494_06535	A0A094BMT3	A0A094AZ72	Fungal_trans domain-containing protein.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.408
V494_02095	V494_07420	A0A094BMT3	A0A094DFR7	Fungal_trans domain-containing protein.	Uncharacterized protein.	0.989
V494_02095	V494_08528	A0A094BMT3	A0A094AQR1	Fungal_trans domain-containing protein.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.985