node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SpoIIR | gpr | A2J09_21355 | A2J09_11650 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | 0.774 |
SpoIIR | sigF_2 | A2J09_21355 | A2J09_02165 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.773 |
SpoIIR | sigK | A2J09_21355 | A2J09_11735 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. | 0.784 |
SpoIIR | spo0A | A2J09_21355 | A2J09_10125 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity). | 0.825 |
SpoIIR | spoIIAA | A2J09_21355 | A2J09_02155 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anti-sigma F factor antagonist; In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition; Belongs to the anti-sigma-factor antagonist family. | 0.927 |
SpoIIR | spoIIAB | A2J09_21355 | A2J09_02160 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.927 |
SpoIIR | spoIVA | A2J09_21355 | A2J09_03150 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | Stage IV sporulation protein B; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
SpoIIR | spoIVB | A2J09_21355 | A2J09_10130 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.803 |
SpoIIR | spoVFB | A2J09_21355 | A2J09_01660 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dipicolinate synthase subunit B; Involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.672 |
SpoIIR | yabP | A2J09_21355 | A2J09_19300 | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sporulation protein YabP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.845 |
gpr | SpoIIR | A2J09_11650 | A2J09_21355 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.774 |
gpr | sigF_2 | A2J09_11650 | A2J09_02165 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.768 |
gpr | sigK | A2J09_11650 | A2J09_11735 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. | 0.847 |
gpr | spo0A | A2J09_11650 | A2J09_10125 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box) (By similarity). | 0.800 |
gpr | spoIIAA | A2J09_11650 | A2J09_02155 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Anti-sigma F factor antagonist; In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition; Belongs to the anti-sigma-factor antagonist family. | 0.772 |
gpr | spoIIAB | A2J09_11650 | A2J09_02160 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.799 |
gpr | spoIVA | A2J09_11650 | A2J09_03150 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Stage IV sporulation protein B; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.811 |
gpr | spoIVB | A2J09_11650 | A2J09_10130 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.831 |
gpr | spoVFB | A2J09_11650 | A2J09_01660 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Dipicolinate synthase subunit B; Involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.638 |
gpr | yabP | A2J09_11650 | A2J09_19300 | GPR endopeptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family. | Sporulation protein YabP; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.787 |