STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANA46379.1dUTPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)    
Predicted Functional Partners:
ANA46380.1
Sigma-w pathway protein ysdB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.727
ANA47872.1
DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.653
ComK
Competence protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.599
ytkD
Nucleoside triphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family.
  
    0.593
yneB
Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.590
ysdC_1
Peptidase M28; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.561
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
 0.546
ANA48035.1
Dithiol-disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.523
spoIIIAH_1
Stage III sporulation protein AH; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.500
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.499
Your Current Organism:
Lysinibacillus sphaericus
NCBI taxonomy Id: 1421
Other names: ATCC 14577, B-23268, BCRC 12825, Bacillus sp. G10(2009), Bacillus sphaericus, CCM 2120, CCRC 12825, CCRC:12825, CCUG 7428, CIP 65.30, DSM 28, IAM 13420, JCM 2502, KCTC 3346, L. sphaericus, LMG 7134, LMG:7134, NBRC 15095, NCCB 75018, NCIMB 9370, NCTC 10338, NRRL B-23268, VKM B-509
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