STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dltBD-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane. (387 aa)    
Predicted Functional Partners:
dltD
D-alanyl-lipoteichoic acid biosynthesis protein DltD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
dltC
D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
 
 
 0.992
dltA
D-alanine--poly(phosphoribitol) ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-de [...]
    0.951
acpA
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.869
ANA45440.1
Petrobactin biosynthesis protein AsbE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.869
ANA45441.1
Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.869
ANA46680.1
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.723
icaA_1
Hyaluronan synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.586
ANA45712.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.528
ANA44737.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.504
Your Current Organism:
Lysinibacillus sphaericus
NCBI taxonomy Id: 1421
Other names: ATCC 14577, B-23268, BCRC 12825, Bacillus sp. G10(2009), Bacillus sphaericus, CCM 2120, CCRC 12825, CCRC:12825, CCUG 7428, CIP 65.30, DSM 28, IAM 13420, JCM 2502, KCTC 3346, L. sphaericus, LMG 7134, LMG:7134, NBRC 15095, NCCB 75018, NCIMB 9370, NCTC 10338, NRRL B-23268, VKM B-509
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.