STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clsCardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (482 aa)    
Predicted Functional Partners:
AMA54231.1
Cardiolipin synthase B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
  
  
 
0.974
AMA54236.1
Cardiolipin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.973
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
 
 
 0.839
mprF
Phosphatidylglycerol lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
  
 0.815
AMA54447.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.580
sufU
Iron-sulfur cluster assembly scaffold protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.547
AMA51367.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.500
AMA52344.1
Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family.
     
 0.494
mycA
Non-ribosomal peptide synthetase; This protein is a multifunctional enzyme, able to activate a long chain fatty acid and link it with the amino acid Asn as part of the synthesis of mycosubtilin. The activation sites consist of individual domains.
   
 0.490
AMA51658.1
Glycerophosphodiester phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.478
Your Current Organism:
Bacillus subtilis inaquosorum
NCBI taxonomy Id: 483913
Other names: B. subtilis subsp. inaquosorum, BGSC 3A28, Bacillus subtilis subsp. inaquosorum, Bacillus subtilis subsp. inaquosorum Rooney et al. 2009, DSM 22148, KCTC 13429, NRRL B-23052
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